Date: 2024-04-15
Title: Adaptive designs in dermatology clinical trials: Current status and future perspectives
Authors: D. Potvin, P. D'Angelo, S. Bennett, J. Jankicevic, R. Bissonnette
Category: Other
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Date: 2024-03-28
Title: A PHASE 1 STUDY OF THE PHARMACOKINETICS OF ADAGRASIB IN SUBJECTS WITH MILD, MODERATE, OR SEVERE RENAL IMPAIRMENT COMPARED TO SUBJECTS WITH NORMAL RENAL FUNCTION.
Authors: C. Cilliers1, P. McCloskey1, J. Morin2, J. Tran1; 1Mirati Therapeutics, 2Innovaderm Research.
Category: Other
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Date: 2024-03-28
Title: A PHASE 1 STUDY OF THE PHARMACOKINETICS OF ADAGRASIB IN SUBJECTS WITH MILD, MODERATE, OR SEVERE HEPATIC IMPAIRMENT COMPARED TO SUBJECTS WITH NORMAL HEPATIC FUNCTION.
Authors: C. Cilliers1, P. McCloskey1, J. Morin2, J. Tran1; 1Mirati Therapeutics, 2Innovaderm Research.
Category: Other
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Date: 2024-02-27
Title: Phase II study investigating the efficacy and safety of glesatinib (MGCD265) in patients with advanced NSCLC containing MET activating alterations
Authors: David S. Hong, Federico Cappuzzo, Byoung Chul Cho, Afshin Dowlati, Maen Hussein, Dong-Wan Kim, Ivor Percent, James G. Christensen, Josée Morin, Diane Potvin, Demiana Faltaos, Vanessa Tassell, Hirak Der-Torossian, Richard Chao
Category: Other
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Date: 2023-12-18
Title: Effect of abrocitinib on skin biomarkers in patients with moderate-to-severe atopic dermatitis
Authors: Guttman-Yassky E, Facheris P, Gomez-Arias PJ, Del Duca E, Da Rosa JC, Weidinger S, Bissonnette R, Armstrong AW, Seneschal J, Eyerich K, Estrada YD, Bose SN, Xu D, Chen A, Tatulych S, Güler E, Chan G, Page KM, Kerkmann U
Category: Dermatitis (all types)
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Date: 2023-12-16
Title: Eligibility Criteria for Active Ulcerative Pyoderma Gangrenosum (PG) in Clinical Trials: A Delphi Consensus on Behalf of the Understanding PG: Review and Assessment of Disease Effects (UPGRADE) Group
Authors: Kamal K, Xia E, Li SJ, Alavi A, Cogen AL, Firooz A, Marzano AV, Kaffenberger BH, Sibbald C, Fernandez AP, Callen JP, Dissemond J, Renato V Gontijo J, Shams K, Gerbens LA, French LE, Gould LJ, Bissonnette R, Shaigany S, Tolkachjov S, Yamamoto T, Wei-Ting Huang W, Ortega-Loayza AG, Mostaghimi A
Category: Other
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Date: 2023-11-27
Title: Baseline Characteristics of Canadian Patients in the Psoriasis Longitudinal Assessment and Registry (PSOLAR)
Authors: Gooderham MJ, Bissonnette R, Kalia S, Papp KA, Guenther LC, Gulliver WP, Ho V, Shear NH, Vender R, Gniadecki R, Prajapati VH, Turchin I, Langholff W, Parnell K, Simpson SD, Abbarin N, Lakhani O, Alhusayen R
Category: Psoriasis
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Date: 2023-11-27
Title: Baseline Characteristics of Canadian Patients in the Psoriasis Longitudinal Assessment and Registry (PSOLAR)
Authors: Gooderham MJ, Bissonnette R, Kalia S, Papp KA, Guenther LC, Gulliver WP, Ho V, Shear NH, Vender R, Gniadecki R, Prajapati VH, Turchin I, Langholff W, Parnell K, Simpson SD, Abbarin N, Lakhani O, Alhusayen R
Category: Psoriasis
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Date: 2023-11-20
Title: Clinical and molecular effects of oral CCR4 antagonist RPT193 in atopic dermatitis: A Phase 1 study
Authors: Bissonnette R, DuBois J, Facheris P, Del Duca E, Kim M, Correa Da Rosa J, Trujillo DL, Bose S, Pagan AD, Wustrow D, Brockstedt DG, Wong B, Kassner PD, Jankicevic J, Ho W, Cheng LE, Guttman-Yassky E
Category: Dermatitis (all types)
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Date: 2023-11-09
Title: The vIGA-AD scale for atopic dermatitis: Uptake in the past 5 years and position of the International Eczema Council
Authors: Bissonnette R, Simpson E, Eichenfield LF, Guttman-Yassky E, Silverberg JI, Beck LA, Mija L, Thyssen JP, Bieber T, Kabashima K, Siegfried E, Stingl G, van de Kerkhof P, Yosipovitch G, Paul C, Paller AS
Category: Dermatitis (all types)
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Date: 2023-09-20
Title: Spesolimab Efficacy and Safety in Patients with Moderate-to-Severe Palmoplantar Pustulosis: A Multicentre, Double-Blind, Randomised, Placebo-Controlled, Phase IIb, Dose-Finding Study
Authors: Burden AD, Bissonnette R, Navarini AA, Murakami M, Morita A, Haeufel T, Ye B, Baehner F, Terui T
Category: Psoriasis
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Date: 2023-09-12
Title: Treat-To-Target in Dermatology: A Scoping Review and International Eczema Council Survey on the Approach in Atopic-Dermatitis
Authors: Renert-Yuval Y, Del Duca E, Arents B, Bissonnette R, Drucker AM, Flohr C, Guttman-Yassky E, Hijnen D, Kabashima K, Leshem YA, Paller AS, Silverberg JI, Simpson EL, Spuls P, Vestergaard C, Wollenberg A, Irvine AD, Thyssen JP
Category: Dermatitis (all types)
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Date: 2023-08-14
Title: Intrapatient comparison of atopic dermatitis skin transcriptome shows differences between tape-strips and biopsies
Authors: Del Duca E, He H, Liu Y, Pagan AD, David E, Cheng J, Carroll B, Renert-Yuval Y, Bar J, Estrada YD, Maari C, Proulx ES, Krueger JG, Bissonnette R, Guttman-Yassky E
Category: Dermatitis (all types)
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Date: 2023-07-07
Title: The Generalized Pustular Psoriasis Physician Global Assessment (GPPGA) score: online assessment and validation study of a specific measure of GPP disease activity
Authors: Burden AD, Bachelez H, Choon SE, Marrakchi S, Tsai TF, Turki H, Morita A, Lebwohl MG, Bissonnette R, Zheng M, Anadkat MJ, Alexander AN, Tang M, Thoma C, Duffin KC
Category: Psoriasis
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Date: 2023-06-13
Title: Tapinarof for psoriasis and atopic dermatitis: 15 years of clinical research
Authors: R. Bissonnette, E. Saint-Cyr Proulx, C. Jack, C. Maari
Category: Dermatitis (all types),Psoriasis
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Date: 2023-06-13
Title: Ethnicity, Race and Skin Color: Challenges and Opportunities for Atopic Dermatitis Clinical Trials
Authors: Robert Bissonnette, Jasmina Jankicevic, Etienne Saint-Cyr Proulx and Catherine Maari
Category: Dermatitis (all types)
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Date: 2023-05-11
Title: Dupilumab inhibits vascular leakage of blood proteins into atopic dermatitis skin
Authors: Leung DYM, Bissonnette R, Kreimer S, Berdyshev E, Bafna S, Lyubchenko T, Richers BN, Garcia S, Ramirez-Gama M, Hall CF, Xiao O, Taylor P, Boguniewicz M, Levit NA, Agueusop I, Zhang A, Goleva E
Category: Dermatitis (all types)
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Date: 2023-05-10
Title: Oral prednisone regulates human skin T cells in delayed-type hypersensitivity reaction elicited by diphencyprone
Authors: Mehta H, Jack C, Maari C, Saint-Cyr Proulx É, Bissonnette R, Ramirez-Valle F, Sarfati M
Category: Other
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Date: 2023-04-23
Title: Oral spleen tyrosine kinase/Janus Kinase inhibitor gusacitinib for the treatment of chronic hand eczema: Results of a randomized phase 2 study
Authors: Jimenez PA, Sofen HL, Bissonnette R, Lee M, Fowler J, Zammit DJ, Chen Y, Rao N, Denis L, Gupta S
Category: Dermatitis (all types)
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Date: 2023-04-21
Title: The Treat-to-Target Project in Atopic Dermatitis: One Year On
Authors: De Bruin-Weller M, Deleuran M, Biedermann T, Bissonnette R, Foley P, Girolomoni G, Hercogová J, Hong CH, Katoh N, Pink A, Richard MA, Shumack S, Silvestre JF, Thyssen JP, Weidinger S
Category: Dermatitis (all types)
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Date: 2023-04-11
Title: Crisaborole reverses dysregulation of the mild to moderate atopic dermatitis proteome towards nonlesional and normal skin
Authors: Madeline Kim, Ester Del Duca, Julia Cheng, Britta Carroll, Paola Facheris, Yeriel Estrada, Amy Cha, John Werth, Robert Bissonnette, Karl Nocka, Chuanbo Zang, Ana B Pavel, Emma Guttman-Yassky
Category: Dermatitis (all types)
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Date: 2023-03-18
Title: Psychometric validation of the generalized pustular psoriasis physician global assessment (GPPGA) and generalized pustular psoriasis area and severity index (GPPASI)
Authors: Burden AD, Bissonnette R, Lebwohl MG, Gloede T, Anatchkova M, Budhiarso I, Hu N, Thoma C, Skalicky AM, Bachelez H
Category: Psoriasis
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Date: 2023-02-25
Title: Estimands for atopic dermatitis clinical trials: expert opinion on the importance of intercurrent events
Authors: Bissonnette R, Eichenfield LF, Simpson E, Thaçi D, Kabashima K, Thyssen JP, Guttman-Yassky E, Nunes FP, Gamalo M, Ahmad F, Kuligowski M, Sun K, Pipper C, Christensen AW, D'Angelo P, Milutinovic M, Guettner A, Silverberg JI
Category: Dermatitis (all types)
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Date: 2023-02-15
Title: NOD2 Agonism Counter-Regulates Human Type 2 T Cell Functions in Peripheral Blood Mononuclear Cell Cultures: Implications for Atopic Dermatitis
Authors: Gimenez-Rivera VA, Patel H, Dupuy FP, Allakhverdi Z, Bouchard C, Madrenas J, Bissonnette R, Piccirillo CA, Jack C
Category: Dermatitis (all types)
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Date: 2023-02-13
Title: Efficacy and safety of etrasimod, a sphingosine 1-phosphate receptor modulator, in adults with moderate-to-severe atopic dermatitis (ADVISE)
Authors: Silverberg JI, Bissonnette R, Kircik L, Murrell DF, Selfridge A, Liu K, Ahluwalia G, Guttman-Yassky E
Category: Dermatitis (all types)
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Date: 2023-02-10
Title: Safety of baricitinib in patients with alopecia areata
Authors: Bissonnette R
Category: Other
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Date: 2023-02-09
Title: Phase 2 Trial of Difelikefalin in Notalgia Paresthetica
Authors: Kim BS, Bissonnette R, Nograles K, Munera C, Shah N, Jebara A, Cirulli J, Goncalves J, Lebwohl M
Category: Other
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Date: 2023-02-08
Title: Mocetinostat in Combination With Durvalumab for Patients With Advanced NSCLC: Results From a Phase I/II Study
Authors: Melissa L. Johnson, James Strauss, Manish R. Patel, Edward B. Garon, Keith D. Eaton, Tavette Neskorik, Josée Morin, Richard Chao, Balazs Halmos
Category: Other
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Date: 2023-02-03
Title: Efficacy and safety of vixarelimab, a human monoclonal oncostatin M receptor β antibody, in moderate-to-severe prurigo nodularis: a randomised, double-blind, placebo-controlled, phase 2a study
Authors: Sofen H, Bissonnette R, Yosipovitch G, Silverberg JI, Tyring S, Loo WJ, Zook M, Lee M, Zou L, Jiang GL, Paolini JF
Category: Other
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Date: 2023-02-01
Title: The Safety and Efficacy of Roflumilast Cream 0.15% and 0.05% in Patients With Atopic Dermatitis: Randomized, Double-Blind, Phase 2 Proof of Concept Study
Authors: Gooderham M, Kircik L, Zirwas M, Lee M, Kempers S, Draelos Z, Ferris L, Jones T, Saint-Cyr Proulx E, Bissonnette R, Bhatia N, Koppel R, Guenthner S, Eads K, Welgus H, Merritt C, Elias M, Navale L, Higham R, Droege M, Berk D
Category: Dermatitis (all types)
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Date: 2023-01-01
Title: Follow-up of Patients With Keratinocyte Carcinoma: A Systematic Review of Clinical Practice Guidelines
Authors: Sara Mirali, Evan Tang, Aaron M Drucker, Irina Turchin, Melinda Gooderham, Nick Levell, Jennifer Beecker, Robert Bissonnette, Helen Catherall, Jo-Ann Lapointe McKenzie, Nicole Hawkins, Chih-Ho Hong, Sunil Kalia, Kim Papp, An-Wen Chan
Category: Other
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Date: 2022-12-13
Title: Real-world evidence on atopic dermatitis: Baseline characteristics and predictors of treatment choice in the TARGET cohort.
Authors: Abuabara K, Eichenfield LF, Bissonnette R, Silverberg JI, Bagel J, Guttman-Yassky E, Thaci D, Simpson EL, Harris JE, Krueger J, Myers DE, Gamelli A, Milutinovic M, Parneix A, Crawford JM, Munoz B, Paller AS
Category: Dermatitis (all types)
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Date: 2022-12-02
Title: Phase I Study Evaluating Glesatinib (MGCD265), An Inhibitor of MET and AXL, in Patients with Non-small Cell Lung Cancer and Other Advanced Solid Tumors
Authors: Christian Kollmannsberger, Herbert Hurwitz, Lyudmila Bazhenova, Byoung Chul Cho, David Hong, Keunchil Park, Karen L. Reckamp, Sunil Sharma, Hirak Der-Torossian, James G. Christensen, Demiana Faltaos, Diane Potvin, Vanessa Tassell, Richard Chao & Geoffrey I. Shapiro
Category: Other
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Date: 2022-11-17
Title: Efficacy of downtitration or treatment withdrawal compared to continuous dosing after successful treatment with baricitinib in patients with moderate-to-severe atopic dermatitis in a randomised substudy from the long-term extension study, BREEZE-AD3
Authors: Kristian Reich, Eric Simpson, Andreas Wollenberg, Robert Bissonnette, Masatoshi Abe, Tracy Cardillo, Jonathan Janes, Luna Sun, Sherry Chen, Jonathan I Silverberg
Category: Dermatitis (all types)
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Date: 2022-11-14
Title: Spesolimab, an anti-interleukin-36 receptor antibody, in patients with moderate-to-severe atopic dermatitis: results from a multicenter, randomized, double-blind, placebo-controlled, phase IIa study
Authors: Bissonnette R, Abramovits W, Saint-Cyr Proulx É, Lee P, Guttman-Yassky E, Zovko E, Sigmund R, Willcox J, Bieber T
Category: Dermatitis (all types)
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Date: 2022-11-02
Title: Follow-up of Patients With Keratinocyte Carcinoma: A Systematic Review of Clinical Practice Guidelines
Authors: Mirali S, Tang E, Drucker AM, Turchin I, Gooderham M, Levell N, Beecker J, Bissonnette R, Catherall H, Lapointe McKenzie JA, Hawkins N, Hong CH, Kalia S, Papp K, Chan AW
Category: Other
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Date: 2022-09-30
Title: Delayed type hypersensitivity reactions to various allergens may differently model inflammatory skin diseases
Authors: Pavel AB, Del Duca E, Cheng J, Wu J, Ungar B, Estrada YD, Jack C, Maari C, Saint-Cyr Proulx É, Ramirez-Valle F, Krueger JG, Bissonnette R, Guttman-Yassky E
Category: Other
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Date: 2022-09-12
Title: Magnitude and Time Course of Response to Abrocitinib for Moderate-to-Severe Atopic Dermatitis
Authors: Reich K, Lio PA, Bissonnette R, Alexis AF, Lebwohl MG, Pink AE, Kabashima K, Boguniewicz M, Nowicki RJ, Valdez H, Zhang F, DiBonaventura M, Cameron MC, Clibborn C
Category: Dermatitis (all types)
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Date: 2022-08-07
Title: Durability of Response to Abrocitinib in Patients with Moderate-to-Severe Atopic Dermatitis After Treatment Discontinuation in a Phase 2b Trial
Authors: Gooderham MJ, Girolomoni G, Moore JO, Silverberg JI, Bissonnette R, Forman S, Peeva E, Biswas P, Valdez H, Chan G
Category: Dermatitis (all types)
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Date: 2022-08-04
Title: Comparison of the Inflammatory Circuits in Psoriasis Vulgaris, Non-Pustular Palmoplantar Psoriasis, and Palmoplantar Pustular Psoriasis
Authors: Wang CQ, Haxhinasto S, Garcet S, Kunjravia N, Cueto I, Gonzalez J, Rambhia D, Harari O, Sleeman MA, Hamilton JD, Lim WK, Freudenberg J, Kalliolias GD, Thakker P, Bissonnette R, Krueger JG
Category: Psoriasis
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Date: 2022-07-11
Title: Dupilumab significantly improves skin barrier function in patients with moderate-to-severe atopic dermatitis
Authors: Berdyshev E, Goleva E, Bissonnette R, Bronova I, Bronoff AS, Richers BN, Garcia S, Ramirez-Gama M, Taylor P, Praestgaard A, Agueusop I, Jurvilliers P, Boguniewicz M, Levit NA, Rossi AB, Zhang A, Leung DYM
Category: Dermatitis (all types)
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Date: 2022-07-01
Title: Improvement of head and neck symptoms in patients with atopic dermatitis treated with baricitinib based on five Phase III clinical trials
Authors: Wollenberg A, Lio P, Kleyn E, Bissonnette R, Jose Rueda M, Casillas M, Chen YF, Lu N, Schloebe A, Simpson E
Category: Dermatitis (all types)
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Date: 2022-06-27
Title: One-Year Safety and Efficacy of Tapinarof Cream for the Treatment of Plaque Psoriasis: Results from the PSOARING 3 Trial
Authors: Strober B, Stein Gold L, Bissonnette R, Armstrong AW, Kircik L, Tyring SK, Piscitelli SC, Brown PM, Rubenstein DS, Tallman AM, Lebwohl MG.J
Category: Psoriasis
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Date: 2022-05-23
Title: A Maximum-Use Trial of Ruxolitinib Cream in Adolescents and Adults with Atopic Dermatitis
Authors: Bissonnette R, Call RS, Raoof T, Zhu Z, Yeleswaram S, Gong X, Lee M
Category: Dermatitis (all types)
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Date: 2022-05-03
Title: Dupilumab Provides Acceptable Safety and Sustained Efficacy for up to 4 Years in an Open-Label Study of Adults with Moderate-to-Severe Atopic Dermatitis
Authors: Beck LA, Deleuran M, Bissonnette R, de Bruin-Weller M, Galus R, Nakahara T, Seo SJ, Khokhar FA, Vakil J, Xiao J, Marco AR, Levit NA, O'Malley JT, Shabbir A
Category: Dermatitis (all types)
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Date: 2022-04-20
Title: The Validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD™): A Clinical Outcome Measure for the Severity of Atopic Dermatitis
Authors: Simpson EL, Bissonnette R, Paller AS, King B, Silverberg JI, Reich K, Thyssen JP, Doll H, Sun L, DeLozier AM, Nunes FP, Eichenfield LF
Category: Dermatitis (all types)
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Date: 2022-04-01
Title: Efficacy and Safety of Upadacitinib in Patients With Moderate to Severe Atopic Dermatitis: Analysis of Follow-up Data From the Measure Up 1 and Measure Up 2 Randomized Clinical Trials
Authors: Simpson EL, Papp KA, Blauvelt A, Chu CY, Hong HC, Katoh N, Calimlim BM, Thyssen JP, Chiou AS, Bissonnette R, Stein Gold LF, Wegzyn C, Hu X, Liu M, Liu J, Tenorio AR, Chu AD, Guttman-Yassky E
Category: Dermatitis (all types)
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Date: 2022-03-15
Title: Systemic Therapy for Atopic Dermatitis in Older Adults and Adults With Comorbidities: A Scoping Review and International Eczema Council Survey
Authors: Drucker AM, Lam M, Flohr C, Thyssen JP, Kabashima K, Bissonnette R, Dlova NC, Aoki V, Chen M, Yu J, Zhu JW, Micieli R, Nosbaum A
Category: Dermatitis (all types)
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Date: 2021-12-09
Title: Phase 3 Trials of Tapinarof Cream for Plaque Psoriasis
Authors: Lebwohl MG, Stein Gold L, Strober B, Papp KA, Armstrong AW, Bagel J, Kircik L, Ehst B, Hong HC, Soung J, Fromowitz J, Guenthner S, Piscitelli SC, Rubenstein DS, Brown PM, Tallman AM, Bissonnette R.
Category: Psoriasis
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Date: 2021-11-01
Title: Effect of Costimulatory Blockade With Abatacept After Ustekinumab Withdrawal in Patients With Moderate to Severe Plaque Psoriasis: The PAUSE Randomized Clinical Trial
Authors: Harris KM, Smilek DE, Byron M, Lim N, Barry WT, McNamara J, Garcet S, Konrad RJ, Stengelin M, Bathala P, Korman NJ, Feldman SR, Boh EE, Barber K, Laumann AE, Helfrich YR, Krueger GG, Sofen H, Bissonnette R, Krueger JG
Category: Psoriasis
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Date: 2021-10-30
Title: A Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study to Evaluate the Efficacy and Safety of RIST4721 in Subjects with Palmoplantar Pustulosis
Authors: Bissonnette R, Maari C, Tsianakas A, Reid D, McCutchan S, Baumgartner S, Mackay J, Bhakta N.
Category: Psoriasis
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Date: 2021-10-19
Title: Pustular psoriasis: Molecular pathways and effects of spesolimab in generalized pustular psoriasis
Authors: Baum P, Visvanathan S, Garcet S, Roy J, Schmid R, Bossert S, Lang B, Bachelez H, Bissonnette R, Thoma C, Krueger JG
Category: Psoriasis
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Date: 2021-10-17
Title: Sensitivity of Clinician-Assessed Efficacy Outcome Measurement Instruments in Trials of Topical Therapies for Atopic Dermatitis: A Systematic Review and Meta-Analysis
Authors: Légaré S, Chagnon M, Palijan A, Kojok K, Bissonnette R
Category: Dermatitis (all types)
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Date: 2021-10-11
Title: Practical Management of Patients with Atopic Dermatitis on Dupilumab
Authors: Papp KA, Hong CH, Lansang MP, Turchin I, Adam DN, Beecker JR, Bissonnette R, Gooderham MJ, Jack C, Joseph M, Lynde CW, Shear NH
Category: Dermatitis (all types)
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Date: 2021-07-14
Title: Inflammatory Skin Disorders: Monocyte-Derived Cells Take Center Stage
Authors: Mehta H, Angsana J, Bissonnette R, Muñoz-Elías EJ, Sarfati M
Category: Dermatitis (all types)
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Date: 2021-06-02
Title: Signal Detection and Methodological Limitations in a Real-World Registry: Learnings from the Evaluation of Long-Term Safety Analyses in PSOLAR
Authors: Bissonnette R, Gottlieb AB, Langley RG, Leonardi CL, Papp KA, Pariser DM, Uy J, Lafferty KP, Langholff W, Fakharzadeh S, Berlin JA, Brouwer ES, Greenspan AJ, Strober BE.
Category: Psoriasis
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Date: 2021-06-01
Title: Long-term Efficacy of Baricitinib in Adults With Moderate to Severe Atopic Dermatitis Who Were Treatment Responders or Partial Responders: An Extension Study of 2 Randomized Clinical Trials
Authors: Silverberg JI, Simpson EL, Wollenberg A, Bissonnette R, Kabashima K, DeLozier AM, Sun L, Cardillo T, Nunes FP, Reich K.
Category: Dermatitis (all types)
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Date: 2021-04-18
Title: Vascular inflammation in moderate-to-severe atopic dermatitis is associated with enhanced Th2 response
Authors: Villani AP, Pavel AB, Wu J, Fernandes M, Maari C, Saint-Cyr Proulx E, Jack C, Glickman J, SeulahChoi, He H, Ungar B, Estrada Y, Kameyama N, Zhang N, Gonzales J, Tardif JC, Krueger JG, Bissonnette R, Guttman-Yassky E.
Category: Dermatitis (all types)
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Date: 2021-04-09
Title: Measuring Atopic Dermatitis Disease Severity: The Potential for Electronic Tools to Benefit Clinical Care
Authors: Maintz L, Bieber T, Bissonnette R, Jack C.
Category: Dermatitis (all types)
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Date: 2021-04-08
Title: Tapinarof in the treatment of psoriasis: A review of the unique mechanism of action of a novel therapeutic aryl hydrocarbon receptor-modulating agent
Authors: Bissonnette R, Stein Gold L, Rubenstein DS, Tallman AM, Armstrong A
Category: Psoriasis
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Date: 2021-04-01
Title: Patient-Reported Symptoms and Disease Impacts in Adults With Moderate-to-Severe Atopic Dermatitis: Results From a Phase 2b Study With Abrocitinib
Authors: Simpson EL, Wollenberg A, Bissonnette R, Silverberg JI, Papacharalambous J, Zhu L, Zhang W, Beebe JS, Vincent M, Peeva E, Bushmakin AG, Cappelleri JC, Chen L, Sikirica V, Xenakis J
Category: Dermatitis (all types)
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Date: 2021-03-04
Title: The preponderance of evidence supports an AhR-dependent mechanism of action of tapinarof.
Authors: Bissonnette R, Gold LS, Rubenstein DS, Tallman AM, Armstrong A
Category: Dermatitis (all types),Psoriasis
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Date: 2021-03-04
Title: Spesolimab, an Anti-Interleukin-36 Receptor Antibody, in Patients with Palmoplantar Pustulosis: Results of a Phase IIa, Multicenter, Double-Blind, Randomized, Placebo-Controlled Pilot Study.
Authors: Mrowietz U, Burden AD, Pinter A, Reich K, Schäkel K, Baum P, Datsenko Y, Deng H, Padula SJ, Thoma C, Bissonnette R
Category: Psoriasis
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Date: 2021-03-01
Title: Folliculitis with tapinarof, when it occurs, is generally mild, self-limiting, and rarely interferes with therapy.
Authors: Bissonnette R, Gold LS, Rubenstein DS, Tallman AM, Armstrong A
Category: Dermatitis (all types),Psoriasis
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Date: 2021-02-15
Title: Baricitinib in patients with moderate-to-severe atopic dermatitis: Results from a randomized monotherapy Phase 3 trial in the United States and Canada (BREEZE-AD5).
Authors: Simpson EL, Forman S, Silverberg JI, Zirwas M, Maverakis E, Han G, Guttman-Yassky E, Marnell D, Bissonnette R, Waibel J, Nunes FP, DeLozier AM, Angle R, Gamalo M, Holzwarth K, Goldblum O, Zhong J, Janes J, Papp K
Category: Dermatitis (all types)
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Date: 2021-01-29
Title: Differential Changes in Inflammatory Mononuclear Phagocyte and T Cell Profiles within Psoriatic Skin during Treatment with Guselkumab versus Secukinumab.
Authors: Mehta H, Mashiko S, Angsana J, Rubio M, Hsieh YM, Maari C, Reich K, Blauvelt A, Bissonnette R, Muñoz-Elías EJ, Sarfati M.
Category: Psoriasis
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Date: 2021-01-28
Title: Biomarkers in atopic dermatitis - a review on behalf of the international eczema council.
Authors: Renert-Yuval Y, Thyssen JP, Bissonnette R, Bieber T, Kabashima K, Hijnen D, Guttman-Yassky E
Category: Dermatitis (all types)
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Date: 2021-01-25
Title: Treat-to-Target in Atopic Dermatitis: An International Consensus on a Set of Core Decision Points for Systemic Therapies.
Authors: De Bruin-Weller M, Biedermann T, Bissonnette R, Deleuran M, Foley P, Girolomoni G, Hercogová J, Hong CH, Katoh N, Pink AE, Richard MA, Shumack S, Silvestre JF, Weidinger S
Category: Dermatitis (all types)
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Date: 2020-11-27
Title: International observational atopic dermatitis cohort to follow natural history and treatment course: TARGET-DERM AD study design and rationale.
Authors: Abuabara K, Silverberg JI, Simpson EL, Paller AS, Eichenfield LF, Bissonnette R, Krueger J, Harris JE, Dalfonso L, Watkins SE, Crawford JM, Thaçi D, Guttman-Yassky E
Category: Dermatitis (all types)
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Date: 2020-11-03
Title: Tapinarof in the treatment of psoriasis: A review of the unique mechanism of action of a novel therapeutic AhR modulating agent (TAMA).
Authors: Bissonnette R, Stein Gold L, Rubenstein DS, Tallman AM, Armstrong A
Category: Psoriasis
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Date: 2020-09-30
Title: Chronic Hand Eczema Guidelines From an Expert Panel of the International Eczema Council
Authors: Silverberg JI, Guttman-Yassky E, Agner T, Bissonnette R, Cohen DE, Simpson E, Wollenberg A, Thyssen JP
Category: Dermatitis (all types)
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Date: 2020-09-14
Title: Pooled safety analysis of baricitinib in adult patients with atopic dermatitis from 8 randomized clinical trials
Authors: Bieber T, Thyssen JP, Reich K, Simpson EL, Katoh N, Torrelo A, De Bruin-Weller M, Thaci D, Bissonnette R, Gooderham M, Weisman J, Nunes F, Brinker D, Issa M, Holzwarth K, Gamalo M, Riedl E, Janes J
Category: Dermatitis (all types)
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Date: 2020-07-09
Title: Tape strips detect distinct immune and barrier profiles in atopic dermatitis and psoriasis
Authors: He H, Bissonnette R, Wu J, Diaz A, Saint-Cyr Proulx E, Maari C, Jack C, Louis M, Estrada Y, Krueger JG, Zhang N, Pavel AB, Guttman-Yassky E
Category: Dermatitis (all types),Psoriasis
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Date: 2020-06-17
Title: Dupilumab Provides Favorable Safety and Sustained Efficacy for Up to 3 Years in an Open-Label Study of Adults With Moderate-to-Severe Atopic Dermatitis
Authors: Beck LA, Thaçi D, Deleuran M, Blauvelt A, Bissonnette R, de Bruin-Weller M, Hide M, Sher L, Hussain I, Chen Z, Khokhar FA, Beazley B, Ruddy M, Patel N, Graham NMH, Ardeleanu M, Shumel B
Category: Dermatitis (all types)
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Date: 2020-04-25
Title: The validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD™): The development and reliability testing of a novel clinical outcome measurement instrument for the severity of atopic dermatitis.
Authors: Simpson E, Bissonnette R, Eichenfield LF, Guttman-Yassky E, King B, Silverberg JI, Beck LA, Bieber T, Reich K, Kabashima K, Seyger M, Siegfried E, Stingl G, Feldman SR, Menter A, van de Kerkhof P, Yosipovitch G, Paul C, Martel P, Dubost-Brama A, Armstrong J, Chavda R, Frey S, Joubert Y, Milutinovic M, Parneix A, Teixeira HD, Lin CY, Sun L, Klekotka P, Nickoloff B, Dutronc Y, Mallbris L, Janes JM, DeLozier AM, Nunes FP, Paller AS
Category: Dermatitis (all types)
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Date: 2020-03-14
Title: ILC2 activation by keratinocyte-derived IL-25 drives IL-13 production at sites of allergic skin inflammation.
Authors: Leyva-Castillo JM, Galand C, Mashiko S, Bissonnette R, McGurk A, Ziegler SF, Dong C, McKenzie ANJ, Sarfati M, Geha RS
Category: Other
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Date: 2020-01-05
Title: Baricitinib in patients with moderate-to-severe atopic dermatitis and inadequate response to topical corticosteroids: results from two randomized monotherapy phase III trials.
Authors: Simpson EL, Lacour JP, Spelman L, Galimberti R, Eichenfield LF, Bissonnette R, King BA, Thyssen JP, Silverberg JI, Bieber T, Kabashima K, Tsunemi Y, Costanzo A, Guttman-Yassky E, Beck LA, Janes JM, DeLozier AM, Gamalo M, Brinker DR, Cardillo T, Nunes FP, Paller AS, Wollenberg A, Reich K
Category: Dermatitis (all types)
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Date: 2019-12-26
Title: Efficacy and Safety of Multiple Dupilumab Dose Regimens After Initial Successful Treatment in Patients With Atopic Dermatitis: A Randomized Clinical Trial.
Authors: Worm M, Simpson EL, Thaçi D, Bissonnette R, Lacour JP, Beissert S, Kawashima M, Ferrándiz C, Smith CH, Beck LA, Chan KC, Chen Z, Akinlade B, Hultsch T, Staudinger H, Gadkari A, Eckert L, Davis JD, Rajadhyaksha M, Graham NMH, Pirozzi G, Stahl N, Yancopoulos GD, Ardeleanu M
Category: Dermatitis (all types)
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Date: 2019-12-03
Title: Vaccination Guidelines for Patients with Immune-mediated Disorders Taking Immunosuppressive Therapies: Executive Summary.
Authors: Papp KA, Haraoui B, Kumar D, Marshall JK, Bissonnette R, Bitton A, Bressler B, Gooderham M, Ho V, Jamal S, Pope JE, Steinhart AH, Vinh DC, Wade J
Category: Other
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Date: 2019-11-13
Title: Crisaborole and atopic dermatitis skin biomarkers: an intrapatient randomized trial
Authors: Bissonnette R, Pavel AB, Diaz A, Werth JL, Zang C, Vranic I, Purohit VS, Zielinski MA, Vlahos B, Estrada YD, Saint-Cyr Proulx E, Ports WC, Guttman-Yassky E
Category: Dermatitis (all types)
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Date: 2019-11-09
Title: Persistence of inflammatory phenotype in residual psoriatic plaques in patients on effective biologic therapy: Residual Psoriatic Plaques After Treatment
Authors: Mashiko S, Edelmayer RM, Bi Y, Olson LM, Wetter JB, Wang J, Maari C, Saint-Cyr Proulx E, Kaimal V, Li X, Salte K, Garcet S, Kannan AK, Huang SM, Cao X, Liu Z, Krueger JG, Sarfati M, Bissonnette R, Smith KM
Category: Psoriasis
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Date: 2019-10-04
Title: Oral Janus kinase/SYK inhibition (ASN002) suppresses inflammation and improves epidermal barrier markers in patients with atopic dermatitis
Authors: Pavel AB, Song T, Kim HJ, Del Duca E, Krueger JG, Dubin C, Peng X, Xu H, Zhang N, Estrada YD, Denis L, Rao N, Gupta S, Zammit DJ, Bissonnette R, Guttman-Yassky E
Category: Dermatitis (all types)
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Date: 2019-10-02
Title: Efficacy and Safety of Oral Janus Kinase 1 Inhibitor Abrocitinib for Patients With Atopic Dermatitis: A Phase 2 Randomized Clinical Trial
Authors: Gooderham MJ, Forman SB, Bissonnette R, Beebe JS, Zhang W, Banfield C, Zhu L, Papacharalambous J, Vincent MS, Peeva E
Category: Dermatitis (all types)
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Date: 2019-09-10
Title: Evidence Review of Topical Calcineurin Inhibitors for the Treatment of Adult Atopic Dermatitis
Authors: Hong CH, Gooderham M, Bissonnette R
Category: Dermatitis (all types)
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Date: 2019-08-12
Title: Incidence of Cardiovascular Events Among Tildrakizumab-Treated Patients with Moderate to Severe Plaque Psoriasis: Pooled Data from 3 Large Randomised Clinical Trials
Authors: Bissonnette R, Fernández-Peñas P, Puig L, Mendelsohn AM, Rozzo SJ, Menter A
Category: Psoriasis
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Date: 2019-07-30
Title: Dupilumab shows long-term safety and efficacy in moderate-to-severe atopic dermatitis patients enrolled in a phase 3 open-label extension study
Authors: Deleuran M, Thaçi D, Beck LA, de Bruin-Weller M, Blauvelt A, Forman S, Bissonnette R, Reich K, Soong W, Hussain I, Foley P, Hide M, Bouaziz JD, Gelfand JM, Sher L, Schuttelaar MLA, Wang C, Chen Z, Akinlade B, Gadkari A, Eckert L, Davis JD, Rajadhyaksha M, Staudinger H, Graham NMH, Pirozzi G, Ardeleanu M
Category: Dermatitis (all types)
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Date: 2019-07-26
Title: Oral JAK/SYK-inhibition (ASN002) suppresses inflammation and improves epidermal barrier markers in atopic dermatitis.
Authors: Pavel AB, Song T, Kim HJ, Del Duca E, Krueger JG, Dubin C, Peng X, Xu H, Zhang N, Estrada YD, Denis L, Rao N, Gupta S, Zammit DJ, Bissonnette R, Guttman-Yassky E
Category: Dermatitis (all types)
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Date: 2019-06-25
Title: IL-4Rα Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis.
Authors: Callewaert C, Nakatsuji T, Knight R, Kosciolek T, Vrbanac A, Kotol P, Ardeleanu M, Hultsch T, Guttman-Yassky E, Bissonnette R, Silverberg JI, Krueger J, Menter A, Graham NMH, Pirozzi G, Hamilton JD, Gallo RL
Category: Dermatitis (all types)
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Date: 2019-06-17
Title: Long-Term Effectiveness and Safety of Up to 48 Weeks' Treatment with Topical Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in the Prevention and Reduction of Atrophic Acne Scars in Moderate and Severe Facial Acne.
Authors: Dréno B, Bissonnette R, Gagné-Henley A, Barankin B, Lynde C, Chavda R, Kerrouche N, Tan J
Category: Acne
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Date: 2019-05-03
Title: Major differences in expression of inflammatory pathways in skin from different body sites of healthy individuals.
Authors: Del Duca E, Pavel AB, Dubin C, Song T, Wallace EB, Peng X, Estrada YD, Xu H, Maari C, Jack C, St-Cyr Proulx E, Krueger JG, Bissonnette R, Guttman-Yassky E
Category: Other
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Date: 2019-03-29
Title: The Oral JAK/SYK Inhibitor ASN002 Demonstrates Efficacy and Improves Associated Systemic Inflammation in Patients with Moderate-to-Severe Atopic Dermatitis: Results from a Randomised, Double-Blind, Placebo-Controlled Study.
Authors: Bissonnette R, Maari C, Forman S, Bhatia N, Lee M, Fowler J, Tyring S, Pariser D, Sofen H, Dhawan S, Zook M, Zammit DJ, Usansky H, Denis L, Rao N, Song T, Pavel AB, Guttman-Yassky E.
Category: Dermatitis (all types)
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Date: 2019-03-12
Title: Optimization of placebo use in clinical trials with systemic treatments for atopic dermatitis: an International Eczema Council survey-based position statement.
Authors: Leshem YA, Bissonnette R, Paul C, Silverberg JI, Irvine AD, Paller AS, Cork MJ, Guttman-Yassky E.
Category: Dermatitis (all types)
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Date: 2019-02-10
Title: GBR 830, an anti-OX40, improves skin gene signatures and clinical scores in patients with atopic dermatitis.
Authors: Guttman-Yassky E, Pavel AB, Zhou L, Estrada YD, Zhang N, Xu H, Peng X, Wen HC, Govas P, Gudi G, Ca V, Fang H, Salhi Y, Back J, Reddy V, Bissonnette R, Maari C, Grossman F, Wolff G.
Category: Dermatitis (all types)
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Date: 2019-02-09
Title: Efficacy and Safety of Mirikizumab (LY3074828) in the Treatment of Moderate-to-Severe Plaque Psoriasis: Results from a Randomised Phase 2 Study.
Authors: Reich K, Rich P, Maari C, Bissonnette R, Leonardi C, Menter A, Igarashi A, Klekotka P, Patel D, Li J, Tuttle J, Morgan-Cox M, Edson-Heredia E, Friedrich S, Papp K; AMAF investigators.
Category: Psoriasis
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Date: 2019-01-08
Title: Phase 2, randomized dose-finding study of tapinarof (GSK2894512 cream) for the treatment of plaque psoriasis.
Authors: Robbins K, Bissonnette R, Maeda-Chubachi T, Ye L, Peppers J, Gallagher K, Kraus JE.
Category: Psoriasis
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Date: 2019-01-01
Title: Human and computational models of atopic dermatitis: A review and perspectives by an expert panel of the International Eczema Council
Authors: Bieber T, Bissonnette R, Brown SJ, Dhar S, Eyerich K, Guttman-Yassky E, Hijnen DJ, Irvine A, Paller AS, Perez White BE, Reynolds NJ, Tanaka RJ, Thyssen JP, Vestergaard C, Werfel T, Wollenberg A
Category: Dermatitis (all types)
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Date: 2018-11-23
Title: Vaccination Guidelines for Patients With Immune-Mediated Disorders on Immunosuppressive Therapies.
Authors: Papp KA, Haraoui B, Kumar D, Marshall JK, Bissonnette R, Bitton A, Bressler B, Gooderham M, Ho V, Jamal S, Pope JE, Steinhart AH, Vinh DC, Wade J.
Category: Other
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Date: 2018-11-16
Title: Approach to the Assessment and Management of Adult Patients With Atopic Dermatitis: A Consensus Document. Section V: Consensus Statements on the Assessment and Management of Adult Patients With Moderate-to-Severe Atopic Dermatitis.
Authors: Hong CH, Gooderham MJ, Albrecht L, Bissonnette R, Dhadwal G, Gniadecki R, Grewal P, Kirchhof MG, Landells I, Lansang P, Lynde CW, Papp KA, Poulin Y, Sussman G, Turchin I, Wiseman M, Yeung J.
Category: Dermatitis (all types)
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Date: 2018-11-16
Title: Approach to the Assessment and Management of Adult Patients With Atopic Dermatitis: A Consensus Document.
Authors: Gooderham MJ, Hong CH, Albrecht L, Bissonnette R, Dhadwal G, Gniadecki R, Grewal P, Kirchhof MG, Landells I, Lansang P, Lynde CW, Papp KA, Poulin Y, Sussman G, Turchin I, Wiseman M, Yeung J.
Category: Dermatitis (all types)
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Date: 2018-11-16
Title: Approach to the Assessment and Management of Adult Patients With Atopic Dermatitis: A Consensus Document. Section II: Tools for Assessing the Severity of Atopic Dermatitis.
Authors: Gooderham MJ, Bissonnette R, Grewal P, Lansang P, Papp KA, Hong CH.
Category: Dermatitis (all types)
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Date: 2018-10-17
Title: The role of phosphodiesterase 4 in the pathophysiology of atopic dermatitis and the perspective for its inhibition.
Authors: Guttman-Yassky E, Hanifin JM, Boguniewicz M, Wollenberg A, Bissonnette R, Purohit V, Kilty I, Tallman AM, Zielinski MA.
Category: Dermatitis (all types)
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Date: 2018-09-19
Title: Ultraviolet B induced immunosuppression is not associated with RANKL upregulation in human skin.
Authors: Saint-Cyr Proulx E, Mashiko S, Maari C, Bolduc C, Nigen S, Sarfati M, Bissonnette R.
Category: Other
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Date: 2018-09-06
Title: The safety and efficacy of four different fixed combination regimens of adapalene 0.1%/benzoyl peroxide 2.5% gel for the treatment of acne vulgaris: results from a randomised controlled study.
Authors: Tan J, Bissonnette R, Gratton D, Kerrouche N, Canosa JM.
Category: Acne
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Date: 2018-09-05
Title: Dupilumab progressively improves systemic and cutaneous abnormalities in atopic dermatitis patients.
Authors: Guttman-Yassky E, Bissonnette R, Ungar B, Suárez-Fariñas M, Ardeleanu M, Esaki H, Suprun M, Estrada Y, Xu H, Peng X, Silverberg JI, Menter A, Krueger JG, Zhang R, Chaudhry U, Swanson B, Graham NMH, Pirozzi G, Yancopoulos GD, Hamilton JDD.
Category: Dermatitis (all types)
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Date: 2018-05-21
Title: Tofacitinib in patients with moderate to severe chronic plaque psoriasis: long-term safety and efficacy in an open-label extension study.
Authors: Valenzuela F, Korman NJ, Bissonnette R, Bakos N, Tsai TF, Harper MK, Ports WC, Tan H, Tallman A, Valdez H, Gardner AC.
Category: Psoriasis
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Date: 2018-05-10
Title: Efficacy and Safety of Ixekizumab in a Randomized, Double-Blinded, Placebo-Controlled Phase 3b Study of Patients with Moderate-to-Severe Genital Psoriasis.
Authors: Ryan C, Menter A, Guenther L, Blauvelt A, Bissonnette R, Meeuwis K, Sullivan J, Cather JC, Yosipovitch G, Gottlieb AB, Merola JF, Callis Duffin K, Fretzin S, Osuntokun OO, Burge R, Naegeli AN, Yang FE, Lin CY, Todd K, Potts Bleakman A; IXORA-Q Study Group.
Category: Psoriasis
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Date: 2018-04-19
Title: Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison.
Authors: Dréno B, Bissonnette R, Gagné-Henley A, Barankin B, Lynde C, Kerrouche N, Tan J.
Category: Acne
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Date: 2018-03-19
Title: Effect of short-term liver X receptor activation on epidermal barrier features in mild to moderate atopic dermatitis: A randomized controlled trial.
Authors: Czarnowicki T, Dohlman AB, Malik K, Antonini D, Bissonnette R, Chan TC, Zhou L, Wen HC, Estrada Y, Xu H, Bryson C, Shen J, Lala D, Ma'ayan A, McGeehan G, Gregg R, Guttman-Yassky E.
Category: Dermatitis (all types)
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Date: 2018-02-14
Title: Secukinumab demonstrates high sustained efficacy and a favourable safety profile in patients with moderate-to-severe psoriasis through 5 years of treatment (SCULPTURE Extension Study).
Authors: Bissonnette R, Luger T, Thaçi D, Toth D, Lacombe A, Xia S, Mazur R, Patekar M, Charef P, Milutinovic M, Leonardi C, Mrowietz U.
Category: Psoriasis
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Date: 2018-02-01
Title: Topical Vitamin E Cream Does Not Prevent Visible Light-Induced Pigmentation.
Authors: Mereniuk A, Marchessault P, Maari C, Bolduc C, Bissonnette R
Category: Other
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Date: 2018-02-01
Title: Systemic Pharmacokinetics, Safety, and Preliminary Efficacy of Topical AhR Agonist Tapinarof: Results of a Phase 1 Study.
Authors: Bissonnette R, Vasist LS, Bullman JN, Collingwood T, Chen G, Maeda-Chubachi T.
Category: Other
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Date: 2018-02-01
Title: JAK inhibitors appear to have a bright future in the treatment of atopic dermatitis.
Authors: Bissonnette R.
Category: Dermatitis (all types)
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Date: 2017-11-15
Title: Apremilast for the treatment of moderate to severe palmoplantar psoriasis: results from a double-blind, placebo-controlled, randomized study
Authors: Bissonnette R, Haydey R, Rosoph L, Lynde CW, Bukhalo M, Fowler J, Delorme I, Gagné-Henley A, Gooderham M, Poulin Y, Barber K, Jenkin P, Landells I, Pariser D.
Category: Psoriasis
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Date: 2017-10-21
Title: A Phase 2a Randomized Controlled Study to Evaluate the Pharmacokinetic, Safety, Tolerability, and Clinical Effect of Topically Applied Umeclidinium in Subjects with Primary Axillary Hyperhidrosis
Authors: Nasir A, Bissonnette R, Maari C, DuBois J, Pene Dumitrescu T, Haddad J, Yamaguchi Y, Dalessandro M.
Category: Other
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Date: 2017-10-01
Title: Evaluation of Risk of Major Adverse Cardiovascular Events With Biologic Therapy in Patients With Psoriasis
Authors: Bissonnette R, Kerdel F, Naldi L, Papp K, Galindo C, Langholff W, Tang KL, Szapary P, Fakharzadeh S, Srivastava B, Goyal K, Gottlieb AB.
Category: Psoriasis
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Date: 2017-10-01
Title: Use of capsule endoscopy to identify lesions suggestive of Crohn's disease in patients with moderate to severe psoriasis
Authors: Bissonnette R, Tamaz R, Bolduc C, Maari C, Robillard C, Nigen S, Delorme I, Lynde C.
Category: Psoriasis
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Date: 2017-08-29
Title: Management of Moderate to Severe Plaque Psoriasis: The Emerging Role of IL-17 Inhibition.
Authors: Bissonnette R, Bourcier M, Gooderham M, Hong CH, Landells I, Lynde C, Papp K, Poulin Y, Vender R, Wiseman MC
Category: Psoriasis
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Date: 2017-08-01
Title: The Static Physician's Global Assessment of Genitalia: A Clinical Outcome Measure for the Severity of Genital Psoriasis
Authors: Merola JF, Bleakman AP, Gottlieb AB, Menter A, Naegeli AN, Bissonnette R, Guenther L, Sullivan J, Meeuwis K, See K, Duffin KC.
Category: Psoriasis
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Date: 2017-07-31
Title: Topical treatment of psoriasis: questionnaire results on topical therapy accessibility and in?uence of body surface area on usage
Authors: Iversen L, Lange MM, Bissonette R, Carvalho AVE, van de Kerkhof PC, Kirby B, Kleyn CE, Lynde CW, van der Walt JM, Wu JJ.
Category: Psoriasis
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Date: 2017-07-15
Title: Increased frequencies of basophils, type 2 innate lymphoid cells and Th2 cells in skin of patients with atopic dermatitis but not psoriasis
Authors: Mashiko S, Mehta H, Bissonnette R, Sarfati M.
Category: Dermatitis (all types)
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Date: 2017-07-01
Title: Persistence of interleukin (IL)-17A+ T lymphocytes and IL-17A expression in treatment-resistant psoriatic plaques despite ustekinumab therapy
Authors: Jack C, Mashiko S, Arbour N, Bissonnette R, Sarfati M.
Category: Psoriasis
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Date: 2017-06-05
Title: Secukinumab Sustains Good Efficacy and Favourable Safety in Moderate to Severe Psoriasis up to 3 Years of Treatment: Results from A Double-Blind Extension Study
Authors: Bissonnette R, Luger T, Thaçi D, Toth D, Messina I, You R, Guana A, Fox T, Papavassilis C, Gilloteau I, Mrowietz U.
Category: Psoriasis
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Date: 2017-06-01
Title: Prospective Study of Pathogenesis of Atrophic Acne Scars and Role of Macular Erythema
Authors: Tan J, Bourdès V, Bissonnette R, Petit B Eng L, Reynier P, Khammari A, Dreno B.
Category: Acne
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Date: 2017-04-03
Title: Adapalene 0.1%/benzoyl peroxide 2.5% gel reduces the risk of atrophic scar formation in moderate inflammatory acne: a split-face randomized controlled trial.
Authors: Dreno B, Tan J, Rivier M, Martel P, Bissonnette R.
Category: Acne
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Date: 2017-03-17
Title: Increase in coronary atherosclerosis severity and the prevalence of coronary artery mixed plaques in patients with psoriasis.
Authors: Bissonnette R, Cademartiti F, Maffei E, Tardif JC.
Category: Psoriasis
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Date: 2017-03-09
Title: TNF-alpha antagonist and vascular inflammation in patients with psoriasis vulgaris: a randomized placebo-controlled study.
Authors: Bissonnette R, Harel F, Krueger JG, Guertin MC, Chabot-Blanchet M, Gonzalez J, Maari C, Delorme I, Lynde CW, Tardif JC.
Category: Psoriasis
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Date: 2017-03-07
Title: Short- and long-term safety outcomes with ixekizumab from 7 clinical trials in psoriasis: Etanercept comparisons and integrated data.
Authors: Strober B, Leonardi C, Papp KA, Mrowietz U, Ohtsuki M, Bissonnette R, Ferris LK, Paul C, Lebwohl M, Braun DK, Mallbris L, Wilhelm S, Xu W, Ljungberg A, Acharya N, Reich K.
Category: Psoriasis
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Date: 2017-02-24
Title: Molecular signatures order the potency of topically applied anti-inflammatory drugs in patients with atopic dermatitis.
Authors: Guttman-Yassky E, Ungar B, Malik K, Dickstein D, Suprun M, Estrada YD, Xu H, Peng X, Oliva M, Todd D, Labuda T, Suarez-Farinas M, Bissonnette R.
Category: Dermatitis (all types)
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Date: 2017-01-08
Title: Palmoplantar pustular psoriasis (PPPP) is characterized by activation of the IL-17A pathway.
Authors: Bissonnette R, Fuentes-Duculan J, Mashiko S, Li X, Bonifacio KM, Cueto I, Suárez-Fariñas M, Maari C, Bolduc C, Nigen S, Sarfati M, Krueger JG.
Category: Psoriasis
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Date: 2017-01-07
Title: Olumacostat glasaretil, a novel topical sebum inhibitor, in the treatment of acne vulgaris: A phase IIa, multicenter, randomized, vehicle-controlled study.
Authors: Bissonnette R, Poulin Y, Drew J, Hofland H, Tan J.
Category: Acne
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Date: 2016-12-06
Title: Use of Lesion Response Rate in Actinic Keratosis Trials.
Authors: Szeimies RM, Atanasov P, Bissonnette R
Category: Actinic Keratoses
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Date: 2016-11-17
Title: Topical tofacitinib for atopic dermatitis: a phase IIa randomized trial.
Authors: Bissonnette R, Papp KA, Poulin Y, Gooderham M, Raman M, Mallbris L, Wang C, Purohit V, Mamolo C, Papacharalambous J, Ports WC.
Category: Dermatitis (all types)
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Date: 2016-11-13
Title: The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, but with Key Differences in Immune Regulatory Genes.
Authors: Kim J, Bissonnette R, Lee J, Correa da Rosa J, Suárez-Fariñas M, Lowes MA, Krueger JG.
Category: Psoriasis
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Date: 2016-10-03
Title: Treatment of plaque psoriasis with an ointment formulation of the Janus kinase inhibitor, tofacitinib: a Phase 2b randomized clinical trial.
Authors: Papp KA, Bissonnette R, Gooderham M, Feldman SR, Iversen L, Soung J, Draelos Z, Mamolo C, Purohit V, Wang C, Ports WC.
Category: Psoriasis
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Date: 2016-08-27
Title: A randomized, double-blind, placebo-controlled, dose-escalation study of the safety and efficacy of INCB039110, an oral janus kinase 1 inhibitor, in patients with stable, chronic plaque psoriasis
Authors: Bissonnette R, Luchi M, Fidelus-Gort R, Jackson S, Zhang H, Flores R, Newton R, Scherle P, Yeleswaram S, Chen X, Menter A.
Category: Psoriasis
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Date: 2016-07-30
Title: Identification of key research needs for topical therapy treatment of psoriasis - a consensus paper by the International Psoriasis Council
Authors: Wu JJ, Lynde CW, Kleyn CE, Iversen L, van der Walt JM, Carvalho A, Kirby B, Bissonnette R
Category: Psoriasis
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Date: 2016-07-16
Title: Topical tofacitinib for atopic dermatitis: A Phase 2a randomised trial
Authors: Bissonnette R, Papp KA, Poulin Y, Gooderham M, Raman M, Mallbris L, Wang C, Purohit V, Mamolo C, Papacharalambous J, Ports WC.
Category: Dermatitis (all types)
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Date: 2016-07-07
Title: Apremilast, an oral phosphodiesterase-4 inhibitor, in the treatment of palmoplantar psoriasis: Results of a pooled analysis from phase II PSOR-005 and phase III Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis (ESTEEM) clinical trials in patients with moderate to severe psoriasis
Authors: Bissonnette R, Pariser DM, Wasel NR, Goncalves J, Day RM, Chen R, Sebastian M
Category: Psoriasis
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Date: 2016-07-02
Title: Correction: Based on Molecular Profiling of Gene Expression, Palmoplantar Pustulosis and Palmoplantar Pustular Psoriasis Are Highly Related Diseases that Appear to Be Distinct from Psoriasis Vulgaris
Authors: Bissonnette R, Suárez-Fariñas M, Li X, Bonifacio KM, Brodmerkel C, Fuentes-Duculan J, Krueger JG.
Category: Psoriasis
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Date: 2016-05-20
Title: Psoriasis and Smoking: A Systematic Literature Review and Meta-Analysis With Qualitative Analysis of Effect of Smoking on Psoriasis Severity
Authors: Richer V, Roubille C, Fleming P, Starnino T, McCourt C, McFarlane A, Siu S, Kraft J, Lynde C, Pope JE, Keeling S, Dutz J, Bessette L, Gulliver WP, Haraoui B, Bissonnette R.
Category: Psoriasis
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Date: 2016-05-13
Title: The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, but with Key Differences in Immune Regulatory Genes
Authors: Kim J, Bissonnette R, Lee J, Correa da Rosa J, Suárez-Fariñas M, Lowes MA, Krueger JG
Category: Psoriasis
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Date: 2016-05-07
Title: Comparative effectiveness of biologic agents for the treatment of psoriasis in a real-world setting: Results from a large, prospective, observational study (Psoriasis Longitudinal Assessment and Registry [PSOLAR]).
Authors: Strober BE, Bissonnette R, Fiorentino D, Kimball AB, Naldi L, Shear NH, Goyal K, Fakharzadeh S, Calabro S, Langholff W, You Y, Galindo C, Lee S, Lebwohl MG
Category: Psoriasis
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Date: 2016-05-06
Title: Based on Molecular Profiling of Gene Expression, Palmoplantar Pustulosis and Palmoplantar Pustular Psoriasis Are Highly Related Diseases that Appear to Be Distinct from Psoriasis Vulgaris
Authors: Bissonnette R, Suárez-Fariñas M, Li X, Bonifacio KM, Brodmerkel C, Fuentes-Duculan J, Krueger JG
Category: Psoriasis
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Date: 2016-05-04
Title: Dr. Roubille, et al reply
Authors: Roubille C, Richer V, Starnino T, McCourt C, McFARLANE A, Fleming P, Siu S, Kraft J, Lynde C, Pope JE, Gulliver W, Keeling S, Dutz J, Bessette L, Bissonnette R, Haraoui B
Category: Other
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Date: 2016-04-06
Title: Systematic review of efficacy of anti-tumor necrosis factor (TNF) therapy in patients with psoriasis previously treated with a different anti-TNF agent
Authors: Yamauchi PS, Bissonnette R, Teixeira HD, Valdecantos WC.
Category: Psoriasis
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Date: 2015-08-14
Title: Randomized Pilot Clinical Trial of Tofacitinib Solution for Plaque Psoriasis: Challenges of the Intra-Subject Study Design.
Authors: Ports WC, Feldman SR, Gupta P, Tan H, Johnson TR, Bissonnette R
Category: Psoriasis
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Date: 2015-07-15
Title: Evidence-based Recommendations for the Management of Comorbidities in Rheumatoid Arthritis, Psoriasis, and Psoriatic Arthritis: Expert Opinion of the Canadian Dermatology-Rheumatology Comorbidity Initiative.
Authors: Roubille C, Richer V, Starnino T, McCourt C, McFarlane A, Fleming P, Siu S, Kraft J, Lynde C, Pope J, Gulliver W, Keeling S, Dutz J, Bessette L, Bissonnette R, Haraoui B
Category: Psoriasis
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Date: 2015-07-09
Title: A Phase 2 Trial of Guselkumab versus Adalimumab for Plaque Psoriasis.
Authors: Gordon KB, Duffin KC, Bissonnette R, Prinz JC, Wasfi Y, Li S, Shen YK, Szapary P, Randazzo B, Reich K
Category: Psoriasis
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Date: 2015-05-16
Title: Secukinumab in psoriasis: randomized, controlled phase 3 trial results assessing the potential to improve treatment response in partial responders (STATURE).
Authors: Thaçi D, Humeniuk J, Frambach Y, Bissonnette R, Goodman JJ, Shevade S, Gong Y, Papavassilis C; STATURE study group
Category: Psoriasis
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Date: 2015-05-08
Title: Evidence that a neutrophil-keratinocyte crosstalk is an early target of IL-17A inhibition in psoriasis.
Authors: Reich K, Papp KA, Matheson RT, Tu JH, Bissonnette R, Bourcier M, Gratton D, Kunynetz RA, Poulin Y, Rosoph LA, Stingl G, Bauer WM, Salter JM, Falk TM, Blödorn-Schlicht NA, Hueber W, Sommer U, Schumacher MM, Peters T, Kriehuber E, Lee DM, Wieczorek GA, Kolbinger F, Bleul CC
Category: Psoriasis
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Date: 2015-05-01
Title: Meta-analysis of tumor necrosis factor inhibitors and glucocorticoids on bone density in rheumatoid arthritis and ankylosing spondylitis trials
Authors: Siu S, Haraoui B, Bissonnette R, Bessette L, Roubille C, Richer V, Starnino T, McCourt C, McFarlane A, Fleming P, Kraft J, Lynde C, Gulliver W, Keeling S, Dutz J, Pope JE
Category: Other
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Date: 2015-04-02
Title: Tofacitinib withdrawal and retreatment in moderate-to-severe chronic plaque psoriasis: a randomized controlled trial
Authors: Bissonnette R, Iversen L, Sofen H, Griffiths CE, Foley P, Romiti R, Bachinsky M, Rottinghaus ST, Tan H, Proulx J, Valdez H, Gupta P, Mallbris L, Wolk R
Category: Psoriasis
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Date: 2015-03-24
Title: IL-23/IL-17A Dysfunction Phenotypes Inform Possible Clinical Effects from Anti-IL-17A Therapies.
Authors: Blauvelt A, Lebwohl MG, Bissonnette R
Category: Other
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Date: 2015-03-16
Title: Human mast cells are major IL-22 producers in patients with psoriasis and atopic dermatitis.
Authors: Mashiko S, Bouguermouh S, Rubio M, Baba N, Bissonnette R, Sarfati M
Category: Psoriasis
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Date: 2015-03-09
Title: Response to: 'drugs and cardiovascular risk in inflammatory arthritis: another case of glucocorticoid-bashing?' by Dr Boers.
Authors: Roubille C, Richer V, Starnino T, McCourt C, McFarlane A, Fleming P, Siu S, Kraft J, Lynde C, Pope J, Gulliver W, Keeling S, Dutz J, Bessette L, Bissonnette R, Haraoui B
Category: Other
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Date: 2015-02-28
Title: A Randomized, blinded assessor study to Evaluate the efFIcacy and safety of etanercept 50 mg once weekly plus as Needed topical agent vs. Etanercept 50 mg twice weekly in patients with moderate to severe plaque psoriasis (REFINE)
Authors: Papp KA, Barber K, Bissonnette R, Bourcier M, Lynde CW, Poulin Y, Shelton J, Toole J, Vieira A, Poulin-Costello M.
Category: Psoriasis
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Date: 2015-01-21
Title: Improvements in patient-reported outcomes in patients with psoriasis receiving etanercept plus topical therapies: results from REFINE.
Authors: Papp KA, Barber K, Bissonnette R, Bourcier M, Lynde CW, Poulin Y, Shelton J, Garces K, Toole J, Poulin-Costello M
Category: Psoriasis
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Date: 2015-01-20
Title: Etanercept for patients with psoriasis who did not respond or who lost their response to adalimumab or infliximab.
Authors: Bissonnette R, Maari C, Barber K, Lynde CW, Vender R
Category: Psoriasis
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Date: 2015-01-05
Title: The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis, psoriasis and psoriatic arthritis: a systematic review and meta-analysis.
Authors: Roubille C, Richer V, Starnino T, McCourt C, McFarlane A, Fleming P, Siu S, Kraft J, Lynde C, Pope J, Gulliver W, Keeling S, Dutz J, Bessette L, Bissonnette R, Haraoui B
Category: Psoriasis
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Date: 2014-12-10
Title: Effect of biologics on depressive symptoms in patients with psoriasis: a systematic review.
Authors: Fleming P, Roubille C, Richer V, Starnino T, McCourt C, McFarlane A, Siu S, Kraft J, Lynde C, Pope JE, Keeling S, Dutz J, Bessette L, Bissonnette R, Haraoui B, Gulliver WP
Category: Psoriasis
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Date: 2014-10-01
Title: Increased expression of IL-17A and limited involvement of IL-23 in patients with palmo-plantar (PP) pustular psoriasis or PP pustulosis; results from a randomised controlled trial.
Authors: Bissonnette R, Nigen S, Langley RG, Lynde CW, Tan J, Fuentes-Duculan J, Krueger JG.
Category: Psoriasis
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Date: 2014-08-28
Title: Changes in serum free testosterone, sleep patterns, and 5-alpha-reductase type I activity influence changes in sebum excretion in female subjects.
Authors: Bissonnette R, Risch JE, McElwee KJ, Marchessault P, Bolduc C, Nigen S, Maari C.
Category: Other
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Date: 2014-08-26
Title: Open-label exploratory study of acitretin for the treatment of severe chronic hand dermatitis.
Authors: Tan J, Maari C, Nigen S, Bolduc C, Bissonnette R.
Category: Dermatitis (all types)
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Date: 2014-07-01
Title: A Randomized, blinded assessor study to Evaluate the efFIcacy and safety of etanercept 50 mg once weekly plus as Needed topical agent vs. Etanercept 50 mg twice weekly in patients with moderate to severe plaque psoriasis (REFINE).
Authors: Papp KA, Barber K, Bissonnette R, Bourcier M, Lynde CW, Poulin Y, Shelton J, Toole J, Vieira A, Poulin-Costello M.
Category: Psoriasis
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Date: 2014-06-01
Title: Treatment of notalgia paresthetica with botulinum toxin A: a double-blind randomized controlled trial.
Authors: Maari C, Marchessault P, Bissonnette R.
Category: Other
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Date: 2013-12-01
Title: Long-term efficacy of ustekinumab in patients with moderate-to-severe psoriasis treated for up to 5 years in the PHOENIX 1 study.
Authors: Kimball AB, Papp KA, Wasfi Y, Chan D, Bissonnette R, Sofen H, Yeilding N, Li S, Szapary P, Gordon KB; PHOENIX 1 Investigators.
Category: Psoriasis
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Date: 2013-11-01
Title: Risk of myocardial infarction in Canadian patients with psoriasis: a retrospective cohort study.
Authors: Levesque A, Lachaine J, Bissonnette R.
Category: Psoriasis
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Date: 2013-07-16
Title: A randomized phase 2a efficacy and safety trial of the topical Janus kinase inhibitor tofacitinib in the treatment of chronic plaque psoriasis.
Authors: Ports WC, Khan S, Lan S, Lamba M, Bolduc C, Bissonnette R, Papp K.
Category: Psoriasis
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Date: 2013-04-13
Title: Consensus recommendations for the treatment of basal cell carcinomas in Gorlin syndrome with topical methylaminolaevulinate-photodynamic therapy.
Authors: Basset-Seguin N, Bissonnette R, Girard C, Haedersdal M, Lear JT, Paul C, Piaserico S.
Category: Other
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Date: 2013-01-01
Title: Effects of the tumor necrosis factor-? antagonist adalimumab on arterial inflammation assessed by positron emission tomography in patients with psoriasis: results of a randomized controlled trial.
Authors: Bissonnette R, Tardif JC, Harel F, Pressacco J, Bolduc C, Guertin MC.
Category: Psoriasis
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Date: 2012-12-26
Title: Efficacy and safety of topical WBI-1001 in patients with mild to moderate psoriasis: results from a randomized double-blind placebo-controlled, phase II trial.
Authors: Bissonnette R, Bolduc C, Maari C, Nigen S, Webster JM, Tang L, Lyle M.
Category: Psoriasis
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Date: 2012-12-06
Title: Short incubation photodynamic therapy with methylaminolevulinate and no occlusion for the treatment of actinic keratoses.
Authors: Bissonnette R, Bolduc C, Maari C, Nigen S.
Category: Actinic Keratoses
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Date: 2012-10-28
Title: Influence of the quantity of sunscreen applied on the ability to protect against ultraviolet-induced polymorphous light eruption.
Authors: Bissonnette R, Nigen S, Bolduc C.
Category: Other
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Date: 2012-09-26
Title: Photodynamic therapy for skin field cancerization: an international consensus. International Society for Photodynamic Therapy in Dermatology.
Authors: Braathen LR, Morton CA, Basset-Seguin N, Bissonnette R, Gerritsen MJ, Gilaberte Y, Calzavara-Pinton P, Sidoroff A, Wulf HC, Szeimies RM.
Category: Other
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Date: 2012-09-19
Title: Effect of adalimumab on sleep parameters in patients with psoriasis and obstructive sleep apnea: a randomized controlled trial.
Authors: Maari C, Bolduc C, Nigen S, Marchessault P, Bissonnette R.
Category: Psoriasis
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Date: 2012-08-23
Title: A randomized study comparing the combination of nbUVB and etanercept to etanercept monotherapy in patients with psoriasis who do not exhibit an excellent response after 12 weeks of etanercept.
Authors: Lynde CW, Gupta AK, Guenther L, Poulin Y, Levesque A, Bissonnette R.
Category: Psoriasis
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Date: 2012-08-11
Title: A randomized controlled study of combination therapy with alefacept and narrow band UVB phototherapy (UVB) for moderate to severe psoriasis: efficacy, onset, and duration of response.
Authors: Lui H, Gulliver W, Tan J, Hong CH, Hull P, Shear NH, Paradiso-Hardy F, Bissonnette R.
Category: Psoriasis
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Date: 2012-07-16
Title: Safety and efficacy of adalimumab for the treatment of severe alopecia areata: case series of three patients.
Authors: Bolduc C, Bissonnette R.
Category: Other
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Date: 2012-06-26
Title: Daylight photodynamic therapy for actinic keratosis: an international consensus: International Society for Photodynamic Therapy in Dermatology.
Authors: Wiegell SR, Wulf HC, Szeimies RM, Basset-Seguin N, Bissonnette R, Gerritsen MJ, Gilaberte Y, Calzavara-Pinton P, Morton CA, Sidoroff A, Braathen LR.
Category: Actinic Keratoses
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Date: 2012-04-16
Title: Efficacy and safety of topical WBI-1001 in patients with mild to severe atopic dermatitis: results from a 12-week, multicentre, randomized, placebo-controlled double-blind trial.
Authors: Bissonnette R, Poulin Y, Zhou Y, Tan J, Hong HC, Webster J, Ip W, Tang L, Lyle M.
Category: Dermatitis (all types)
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Date: 2012-02-26
Title: Psoriasis: Why Does it Come With a Greater Risk of Heart Attack and Stroke?
Authors: Bissonnette, R.
Category: Psoriasis
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Date: 2012-02-06
Title: Assessment of the long-term safety and effectiveness of etanercept for the treatment of psoriasis in an adult population.
Authors: Papp KA, Poulin Y, Bissonnette R, Bourcier M, Toth D, Rosoph L, Poulin-Costello M, Setterfield M, Syrotuik J.
Category: Psoriasis
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Date: 2011-12-25
Title: Treatment of palmoplantar psoriasis with infliximab: a randomized, double-blind placebo-controlled study.
Authors: Bissonnette R, Poulin Y, Guenther L, Lynde CW, Bolduc C, Nigen S.
Category: Psoriasis
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Date: 2011-12-14
Title: Treatment of acne with photodynamic therapy.
Authors: Bissonnette R.
Category: Acne
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Date: 2011-11-08
Title: Fatigue and quality of sleep in patients with immune-mediated inflammatory disease.
Authors: Graff LA, Walker JR, Russell AS, Bissonnette R, Bernstein CN.
Category: Other
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Date: 2011-11-08
Title: Validity of quality of life measurement tools--from generic to disease-specific.
Authors: Wells GA, Russell AS, Haraoui B, Bissonnette R, Ware CF.
Category: Other
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Date: 2011-11-03
Title: Socioeconomic burden of immune-mediated inflammatory diseases--focusing on work productivity and disability.
Authors: Jacobs P, Bissonnette R, Guenther LC.
Category: Other
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Date: 2011-09-10
Title: Randomized trial comparing a chemical peel containing a lipophilic hydroxy acid derivative of salicylic acid with a salicylic acid peel in subjects with comedonal acne.
Authors: Levesque A, Hamzavi I, Seite S, Rougier A, Bissonnette R.
Category: Acne
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Date: 2011-08-15
Title: Support needed to involve psoriasis patients in treatment decisions: survey of dermatologists.
Authors: Tan J, Stacey D, Barankin B, Bissonnette R, Gulliver W, Lui H, Shear N, Bhatti S.
Category: Psoriasis
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Date: 2011-05-15
Title: Short incubation methylaminolevulinate photodynamic therapy without occlusion for the treatment of actinic keratoses
Authors: Robert Bissonnette, MD, FRCPC Simon Nigen, MD, FRCPC Chantal Bolduc, MD, FRCPC Catherine Maari, MD, FRCPC
Category: Actinic Keratoses
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Date: 2011-03-03
Title: An open-label study assessing the safety and efficacy of alitretinoin in patients with severe chronic hand eczema unresponsive to topical corticosteroids.
Authors: Dirschka T, Reich K, Bissonnette R, Maares J, Brown T, Diepgen TL.
Category: Dermatitis (all types)
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Date: 2010-12-14
Title: Canadian hand dermatitis management guidelines.
Authors: Lynde C, Guenther L, Diepgen TL, Sasseville D, Poulin Y, Gulliver W, Agner T, Barber K, Bissonnette R, Ho V, Shear NH, Toole J.
Category: Dermatitis (all types)
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Date: 2010-11-09
Title: Photodynamic therapy with methylaminolevulinate 80 mg/g without occlusion improves acne vulgaris.
Authors: Bissonnette R, Maari C, Nigen S, Provost N, Bolduc C.
Category: Acne
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Date: 2010-10-14
Title: Treatment decision needs of psoriasis patients: cross-sectional survey.
Authors: Tan J, Stacey D, Fung K, Barankin B, Bissonnette R, Gulliver W, Lui H, Shear N, Jackson C, Zhang X.
Category: Psoriasis
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Date: 2010-07-04
Title: Safety profile of intravenous and subcutaneous siplizumab, an anti-CD2 monoclonal antibody, for the treatment of plaque psoriasis: results of two randomized, double-blind, placebo-controlled studies.
Authors: Langley RG, Papp K, Bissonnette R, Toth D, Matheson R, Hultquist M, White B.
Category: Psoriasis
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Date: 2010-05-24
Title: Redefining treatment options in chronic hand eczema (CHE).
Authors: Bissonnette R, Diepgen TL, Elsner P, English J, Graham-Brown R, Homey B, Luger T, Lynde C, Maares J, Maibach HI.
Category: Dermatitis (all types)
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Date: 2010-05-21
Title: Clobetasol propionate shampoo 0.05% is efficacious and safe for long-term control of moderate scalp psoriasis.
Authors: Poulin Y, Papp K, Bissonnette R, Barber K, Kerrouche N, Villemagne H; Calepso Study Team.
Category: Psoriasis
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Date: 2010-05-20
Title: Efficacy and safety of adalimumab in patients with plaque psoriasis who have shown an unsatisfactory response to etanercept.
Authors: Bissonnette R, Bolduc C, Poulin Y, Guenther L, Lynde CW, Maari C.
Category: Psoriasis
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Date: 2010-04-14
Title: Efficacy and safety of topical WBI-1001 in the treatment of atopic dermatitis: results from a phase 2A, randomized, placebo-controlled clinical trial.
Authors: Bissonnette R, Chen G, Bolduc C, Maari C, Lyle M, Tang L, Webster J, Zhou Y.
Category: Dermatitis (all types)
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Date: 2010-03-09
Title: A double-blind study of tolerance and efficacy of a new urea-containing moisturizer in patients with atopic dermatitis.
Authors: Bissonnette R, Maari C, Provost N, Bolduc C, Nigen S, Rougier A, Seite S.
Category: Dermatitis (all types)
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Date: 2010-03-06
Title: A randomized, double-blind, placebo-controlled, phase I study of MEDI-545, an anti-interferon-alfa monoclonal antibody, in subjects with chronic psoriasis.
Authors: Bissonnette R, Papp K, Maari C, Yao Y, Robbie G, White WI, Le C, White B.
Category: Psoriasis
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Date: 2010-02-01
Title: Successful retreatment with alitretinoin in patients with relapsed chronic hand eczema.
Authors: Bissonnette R, Worm M, Gerlach B, Guenther L, Cambazard F, Ruzicka T, Maares J, Brown TC.
Category: Dermatitis (all types)
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Date: 2010-01-08
Title: Clobetasol propionate shampoo 0.05% is efficacious and safe for long-term control of scalp psoriasis.
Authors: Poulin Y, Papp K, Bissonnette R, Guenther L, Tan J, Lynde C, Kerrouche N, Villemagne H; CalePso Study Team.
Category: Psoriasis
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Date: 2009-12-13
Title: The next phase of real-world clinical experience with alefacept: the AWARE-2 registry
Authors: Searles G, Bissonnette R, Landells I, Shear NH.
Category: Other
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Date: 2009-12-13
Title: Efficacy outcomes in patients using alefacept in the AWARE study
Authors: Landells I, Searles G, Bissonnette R, Shear NH, Vender R, Lui H.
Category: Other
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Date: 2009-12-13
Title: Patterns of combination therapy with alefacept for the treatment of psoriasis in Canada in the AWARE study
Authors: Searles G, Bissonnette R, Landells I, Shear NH, Papp K, Lui H.
Category: Psoriasis
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Date: 2009-12-13
Title: Update on alefacept safety
Authors: Wexler D, Searles G, Landells I, Shear NH, Bissonnette R, Papp K, Poulin Y, Langley R, Gulliver WP.
Category: Psoriasis
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Date: 2009-12-13
Title: Preface: real-world clinical experience with alefacept-the Amevive Wisdom Acquired from Real-World Evidence (AWARE) study
Authors: Searles G, Bissonnette R, Landells I, Shear NH.
Category: Other
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Date: 2009-12-13
Title: The AWARE study: methodology and baseline characteristics.
Authors: Bissonnette R, Searles G, Landells I, Shear NH, Papp K, Lui H, Gulliver WP, Lynde C.
Category: Other
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Date: 2009-10-13
Title: Safety of conventional systemic agents and biologic agents in the treatment of psoriasis.
Authors: Bissonnette R, Ho V, Langley RG.
Category: Psoriasis
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Date: 2009-07-30
Title: Humanized anti-CD2 monoclonal antibody treatment of plaque psoriasis: efficacy and pharmacodynamic results of two randomized, double-blind, placebo-controlled studies of intravenous and subcutaneous siplizumab.
Authors: Bissonnette R, Langley RG, Papp K, Matheson R, Toth D, Hultquist M, Geba GP, White B.
Category: Psoriasis
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Date: 2009-03-08
Title: Randomized study comparing the efficacy and tolerance of a lipophillic hydroxy acid derivative of salicylic acid and 5% benzoyl peroxide in the treatment of facial acne vulgaris.
Authors: Bissonnette R, Bolduc C, Seité S, Nigen S, Provost N, Maari C, Rougier A.
Category: Acne
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Date: 2008-10-12
Title: Efficacy and tolerability of topical tacrolimus ointment for the treatment of male genital psoriasis.
Authors: Bissonnette R, Nigen S, Bolduc C
Category: Psoriasis
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Date: 2008-10-07
Title: Etanercept in the treatment of palmoplantar pustulosis.
Authors: Bissonnette R, Poulin Y, Bolduc C, Maari C, Provost N, Syrotuik J, Poulin-Costello CM, Nigen S.
Category: Other
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Date: 2008-09-15
Title: Protection afforded by sunscreens containing inorganic sunscreening agents against blue light sensitivity induced by aminolevulinic acid
Authors: Bissonnette R, Nigen S, Bolduc C, Méry S., Nocera T.
Category: Acne
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Date: 2008-06-12
Title: Open-label study to assess the safety and efficacy of imiquimod 5% cream applied once daily three times per week in cycles for treatment of actinic keratoses on the head.
Authors: Rivers JK, Rosoph L, Provost N, Bissonnette R.
Category: Actinic Keratoses
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Date: 2008-04-19
Title: Efficacy of ISA247 in plaque psoriasis: a randomised, multicentre, double-blind, placebo-controlled phase III study.
Authors: Papp K, Bissonnette R, Rosoph L, Wasel N, Lynde CW, Searles G, Shear NH, Huizinga RB, Maksymowych WP.
Category: Psoriasis
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Date: 2008-04-15
Title: Efficacy and safety of oral alitretinoin (9-cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double-blind, placebo-controlled, multicentre trial.
Authors: Ruzicka T, Lynde CW, Jemec GB, Diepgen T, Berth-Jones J, Coenraads PJ, Kaszuba A, Bissonnette R, Varjonen E, Holló P, Cambazard F, Lahfa M, Elsner P, Nyberg F, Svensson A, Brown TC, Harsch M, Maares J.
Category: Dermatitis (all types)
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Date: 2004-02-03
Title: Large surface photodynamic therapy with aminolevulinic acid: treatment of actinic keratoses and beyond
Authors: Bergeron A, Bissonnette R, Liu Y
Category: Actinic Keratoses
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