INNOVADERM CRO IS NOW INDERO.
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Atopic Dermatitis (AD) Case Study

Indero

Indero

Team of Experts

Outcomes

  • Innovaderm successfully managed this AD study and this resulted in enrollment completed 2 months earlier than planned; Innovaderm CRU recruited 33% of patients

Study Characteristics

  • Study Phase: Ib
  • Patient Population: 36 subjects with moderate to severe AD
  • IP Route of Administration: Systemic – Oral
  • Site distribution: 10 sites in 2 countries (USA and Canada)
  • Study Design: Randomized, sequential, placebo-controlled, double-blind | Multiple ascending dose (MAD): 3 sequential cohorts
  • Study procedures: 4.5 mm punch skin biopsies, photographs, biomarker analysis, skin microbiome, pharmacokinetics, tape stripping and efficacy-safety assessments

Study Challenges

  • Recruitment during summer months; Seasonality impacts on AD flares
  • Short treatment duration; 4-week treatment period
  • Data and Safety Monitoring Board (DSMB) after each cohort; Challenging to manage without affecting recruitment

Key Success Factors & Strategies

  • Recruitment completed in 6 months vs planned 8 months
  • Outstanding contribution by Innovaderm’s Clinical Research Unit

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Is Now

We are excited to announce that Innovaderm is rebranding our CRO division as Indero (in-dAIR-oh). This rebranding reflects our ongoing commitment to innovation and our expansion into the field of rheumatology, a therapeutic area closely linked to dermatology. As a dual-focus CRO specializing in both dermatology and rheumatology, this strategic decision marks a significant milestone for our organization, and we are eager to embark on this new chapter with our valued partners and clients. Additionally, our Clinical Research Unit (CRU) will keep the name Innovaderm and will continue to conduct dermatology studies.

Site Selection & Management

Our long-standing relationships with key opinion leaders and highly performing sites, result in optimized start-up processes that deliver strong results in the least amount of time. As part of our site evaluation, our team utilizes past performance metrics, recruitment projections based on competitive landscape, and detailed feasibility surveys to determine a site’s capabilities and interest in a study.

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Patient Recruitment

Our dedicated patient recruitment and advertising team integrates with the study team to tailor recruitment strategies, customize central ad campaigns, develop advertising creative, and continuously track and adapt recruitment goals. Our patient-centric approach is enhanced by Clinago, our technology enabled recruitment service.

PROJECT MANAGEMENT

We orchestrate all study activities and deliverables, including site selection process, budget and contract negotiations, and patient engagement, recruitment enrollment projections, all while respecting your study timelines.

PROJECT MANAGEMENT

We orchestrate all study activities and deliverables, including site selection process, budget and contract negotiations, and patient engagement, recruitment enrollment projections, all while respecting your study timelines.