Publications

Date: September 10, 2019

Title: Evidence Review of Topical Calcineurin Inhibitors for the Treatment of Adult Atopic Dermatitis

Authors: Bissonnette R, Gooderham M, Hong CH

Category: Dermatitis (all types)


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Date: August 13, 2019

Title: Crisaborole and atopic dermatitis skin biomarkers: an intrapatient randomized trial

Authors: Bissonnette R, Diaz A, Estrada YD, Guttman-Yassky E, Pavel AB, Ports WC, Purohit VS, Saint-Cyr Proulx E, Vlahos B, Vranic I, Werth JL, Zang C, Zielinski MA

Category: Dermatitis (all types)


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Date: August 12, 2019

Title: Incidence of Cardiovascular Events Among Tildrakizumab-Treated Patients with Moderate to Severe Plaque Psoriasis: Pooled Data from 3 Large Randomised Clinical Trials

Authors: Bissonnette R, Fernández-Peñas P, Mendelsohn AM, Menter A, Puig L, Rozzo SJ

Category: Psoriasis


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Date: July 30, 2019

Title: Dupilumab shows long-term safety and efficacy in moderate-to-severe atopic dermatitis patients enrolled in a phase 3 open-label extension study

Authors: Akinlade B, Ardeleanu M, Beck LA, Bissonnette R, Blauvelt A, Bouaziz JD, Chen Z, Davis JD, de Bruin-Weller M, Deleuran M, Eckert L, Foley P, Forman S, Gadkari A, Gelfand JM, Graham NMH, Hide M, Hussain I, Pirozzi G, Rajadhyaksha M, Reich K, Schuttelaar MLA, Sher L, Soong W, Staudinger H, Thaçi D, Wang C

Category: Dermatitis (all types)


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Date: July 26, 2019

Title: Oral JAK/SYK-inhibition (ASN002) suppresses inflammation and improves epidermal barrier markers in atopic dermatitis.

Authors: Bissonnette R, Del Duca E, Denis L, Dubin C, Estrada Y, Gupta S, Guttman-Yassky E, Kim HJ, Krueger JG, Pavel AB, Peng X, Rao N, Song T, Xu H, Zammit DJ, Zhang N

Category: Dermatitis (all types)


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Date: June 25, 2019

Title: IL-4Rα Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis.

Authors: Ardeleanu M, Bissonnette R, Callewaert C, Gallo RL, Graham NMH, Guttman-Yassky E, Hamilton JD, Hultsch T, Knight R, Kosciolek T, Kotol P, Krueger J, Menter A, Nakatsuji T, Pirozzi G, Silverberg JI, Vrbanac A

Category: Dermatitis (all types)


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Date: June 17, 2019

Title: Long-Term Effectiveness and Safety of Up to 48 Weeks' Treatment with Topical Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in the Prevention and Reduction of Atrophic Acne Scars in Moderate and Severe Facial Acne.

Authors: Barankin B, Bissonnette R, Chavda R, Dreno B, Gagné-Henley A, Kerrouche N, Lynde C, Tan J

Category: Acne


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Date: May 3, 2019

Title: Major differences in expression of inflammatory pathways in skin from different body sites of healthy individuals.

Authors: Bissonnette R, Brezinski Wallace E, Del Duca E, Dubin C, Estrada YD, Guttman-Yassky E, Jack C, Krueger JG, Maari C, Pavel AB, Peng X, Song T, St-Cyr Proulx E, Xu H

Category: Other


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Date: March 29, 2019

Title: The Oral JAK/SYK Inhibitor ASN002 Demonstrates Efficacy and Improves Associated Systemic Inflammation in Patients with Moderate-to-Severe Atopic Dermatitis: Results from a Randomised, Double-Blind, Placebo-Controlled Study.

Authors: Bissonnette R, Maari C, Forman S, Bhatia N, Lee M, Fowler J, Tyring S, Pariser D, Sofen H, Dhawan S, Zook M, Zammit DJ, Usansky H, Denis L, Rao N, Song T, Pavel AB, Guttman-Yassky E

Category: Dermatitis (all types)


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Date: March 13, 2019

Title: Optimization of placebo use in clinical trials with systemic treatments for atopic dermatitis: an International Eczema Council survey-based position statement.

Authors: Leshem YA, Bissonnette R, Paul C, Silverberg JI, Irvine AD, Paller AS, Cork MJ, Guttman-Yassky E

Category: Dermatitis (all types)


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Date: February 10, 2019

Title: GBR 830, an anti-OX40, improves skin gene signatures and clinical scores in patients with atopic dermatitis.

Authors: Guttman-Yassky E, Pavel AB, Zhou L, Estrada YD, Zhang N, Xu H, Peng X, Wen HC, Govas P, Gudi G, Ca V, Fang H, Salhi Y, Back J, Reddy V, Bissonnette R, Maari C, Grossman F, Wolff G

Category: Dermatitis (all types)


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Date: February 9, 2019

Title: Efficacy and Safety of Mirikizumab (LY3074828) in the Treatment of Moderate-to-Severe Plaque Psoriasis: Results from a Randomised Phase 2 Study.

Authors: Reich K, Rich P, Maari C, Bissonnette R, Leonardi C, Menter A, Igarashi A, Klekotka P, Patel D, Li J, Tuttle J, Morgan-Cox M, Edson-Heredia E, Friedrich S, Papp K; AMAF investigators

Category: Psoriasis


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Date: February 3, 2019

Title: Vaccination Guidelines for Patients with Immune-mediated Disorders Taking Immunosuppressive Therapies: Executive Summary.

Authors: Papp KA, Haraoui B, Kumar D, Marshall JK, Bissonnette R, Bitton A, Bressler B, Gooderham M, Ho V, Jamal S, Pope JE, Steinhart AH, Vinh DC, Wade J

Category: Other


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Date: January 8, 2019

Title: Phase 2, randomized dose-finding study of tapinarof (GSK2894512 cream) for the treatment of plaque psoriasis.

Authors: Robbins K, Bissonnette R, Maeda-Chubachi T, Ye L, Peppers J, Gallagher K, Kraus JE

Category: Psoriasis


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Date: January 1, 2019

Title: Human and computational models of atopic dermatitis: A review and perspectives by an expert panel of the International Eczema Council

Authors: Bieber T, Bissonette R, Brown SJ, Dhar S, Eyerich K, Guttman-Yassky E, Hijnen DJ, Irvine A, Paller AS, Perez White BE, Reynolds NJ, Tanaka RJ, Thyssen JP, Vestergaard C, Werfel T, Wollenberg A

Category: Dermatitis (all types)


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Date: November 23, 2018

Title: Vaccination Guidelines for Patients With Immune-Mediated Disorders on Immunosuppressive Therapies.

Authors: Papp KA, Haraoui B, Kumar D, Marshall JK, Bissonnette R, Bitton A, Bressler B, Gooderham M, Ho V, Jamal S, Pope JE, Steinhart AH, Vinh DC, Wade J

Category: Other


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Date: November 16, 2018

Title: Approach to the Assessment and Management of Adult Patients With Atopic Dermatitis: A Consensus Document. Section V: Consensus Statements on the Assessment and Management of Adult Patients With Moderate-to-Severe Atopic Dermatitis.

Authors: Hong CH, Gooderham MJ, Albrecht L, Bissonnette R, Dhadwal G, Gniadecki R, Grewal P, Kirchhof MG, Landells I, Lansang P, Lynde CW, Papp KA, Poulin Y, Sussman G, Turchin I, Wiseman M, Yeung J

Category: Dermatitis (all types)


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Date: November 16, 2018

Title: Approach to the Assessment and Management of Adult Patients With Atopic Dermatitis: A Consensus Document.

Authors: Gooderham MJ, Hong CH, Albrecht L, Bissonnette R, Dhadwal G, Gniadecki R, Grewal P, Kirchhof MG, Landells I, Lansang P, Lynde CW, Papp KA, Poulin Y, Sussman G, Turchin I, Wiseman M, Yeung J

Category: Dermatitis (all types)


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Date: November 16, 2018

Title: Approach to the Assessment and Management of Adult Patients With Atopic Dermatitis: A Consensus Document. Section II: Tools for Assessing the Severity of Atopic Dermatitis.

Authors: Gooderham MJ, Bissonnette R, Grewal P, Lansang P, Papp KA, Hong CH

Category: Dermatitis (all types)


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Date: October 17, 2018

Title: The role of phosphodiesterase 4 in the pathophysiology of atopic dermatitis and the perspective for its inhibition.

Authors: Guttman-Yassky E, Hanifin JM, Boguniewicz M, Wollenberg A, Bissonnette R, Purohit V, Kilty I, Tallman AM, Zielinski MA

Category: Dermatitis (all types)


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Date: September 19, 2018

Title: Ultraviolet B induced immunosuppression is not associated with RANKL upregulation in human skin.

Authors: Saint-Cyr Proulx E, Mashiko S, Maari C, Bolduc C, Nigen S, Sarfati M, Bissonnette R

Category: Other


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Date: September 6, 2018

Title: The safety and efficacy of four different fixed combination regimens of adapalene 0.1%/benzoyl peroxide 2.5% gel for the treatment of acne vulgaris: results from a randomised controlled study.

Authors: Tan J, Bissonnette R, Gratton D, Kerrouche N, Canosa JM

Category: Acne


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Date: September 5, 2018

Title: Dupilumab progressively improves systemic and cutaneous abnormalities in atopic dermatitis patients.

Authors:

Category: Dermatitis (all types)


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Date: May 21, 2018

Title: Tofacitinib in patients with moderate to severe chronic plaque psoriasis: long-term safety and efficacy in an open-label extension study.

Authors: Valenzuela F, Korman NJ, Bissonnette R, Bakos N, Tsai TF, Harper MK, Ports WC, Tan H, Tallman A, Valdez H, Gardner AC

Category: Psoriasis


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Date: May 10, 2018

Title: Efficacy and Safety of Ixekizumab in a Randomized, Double-Blinded, Placebo-Controlled Phase 3b Study of Patients with Moderate-to-Severe Genital Psoriasis.

Authors:

Category: Psoriasis


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Date: April 19, 2018

Title: Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison.

Authors: Dréno B, Bissonnette R, Gagné-Henley A, Barankin B, Lynde C, Kerrouche N, Tan J

Category: Acne


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Date: March 19, 2018

Title: Effect of short-term liver X receptor activation on epidermal barrier features in mild to moderate atopic dermatitis: A randomized controlled trial.

Authors: Czarnowicki T, Dohlman AB, Malik K, Antonini D, Bissonnette R, Chan TC, Zhou L, Wen HC, Estrada Y, Xu H, Bryson C, Shen J, Lala D, Ma'ayan A, McGeehan G, Gregg R, Guttman-Yassky E

Category: Dermatitis (all types)


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Date: February 14, 2018

Title: Secukinumab demonstrates high sustained efficacy and a favourable safety profile in patients with moderate-to-severe psoriasis through 5 years of treatment (SCULPTURE Extension Study).

Authors: Bissonnette R, Luger T, Thaçi D, Toth D, Lacombe A, Xia S, Mazur R, Patekar M, Charef P, Milutinovic M, Leonardi C, Mrowietz U

Category: Psoriasis


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Date: February 1, 2018

Title: Topical Vitamin E Cream Does Not Prevent Visible Light-Induced Pigmentation.

Authors: Mereniuk A, Marchessault P, Maari C, Bolduc C, Bissonnette R

Category: Other


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Date: February 1, 2018

Title: Systemic Pharmacokinetics, Safety, and Preliminary Efficacy of Topical AhR Agonist Tapinarof: Results of a Phase 1 Study.

Authors: Bissonnette R, Vasist LS, Bullman JN, Collingwood T, Chen G, Maeda-Chubachi T

Category: Other


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Date: February 1, 2018

Title: JAK inhibitors appear to have a bright future in the treatment of atopic dermatitis.

Authors: Bissonnette R

Category: Dermatitis (all types)


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Date: November 15, 2017

Title: Apremilast for the treatment of moderate to severe palmoplantar psoriasis: results from a double-blind, placebo-controlled, randomized study

Authors: Bissonnette R, Haydey R, Rosoph L, Lynde CW, Bukhalo M, Fowler J, Delorme I, Gagné-Henley A, Gooderham M, Poulin Y, Barber K, Jenkin P, Landells I, Pariser D

Category: Psoriasis


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Date: October 21, 2017

Title: A Phase 2a Randomized Controlled Study to Evaluate the Pharmacokinetic, Safety, Tolerability, and Clinical Effect of Topically Applied Umeclidinium in Subjects with Primary Axillary Hyperhidrosis

Authors: Nasir A, Bissonnette R, Maari C, DuBois J, Pene Dumitrescu T, Haddad J, Yamaguchi Y, Dalessandro M

Category: Other


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Date: October 1, 2017

Title: Evaluation of Risk of Major Adverse Cardiovascular Events With Biologic Therapy in Patients With Psoriasis

Authors: Bissonnette R, Kerdel F, Naldi L, Papp K, Galindo C, Langholff W, Tang KL, Szapary P, Fakharzadeh S, Srivastava B, Goyal K, Gottlieb AB

Category: Psoriasis


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Date: October 1, 2017

Title: Use of capsule endoscopy to identify lesions suggestive of Crohn's disease in patients with moderate to severe psoriasis

Authors: Bissonnette R, Tamaz R, Bolduc C, Maari C, Robillard C, Nigen S, Delorme I, Lynde C

Category: Psoriasis


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Date: August 29, 2017

Title: Management of Moderate to Severe Plaque Psoriasis: The Emerging Role of IL-17 Inhibition.

Authors: Bissonnette R, Bourcier M, Gooderham M, Hong CH, Landells I, Lynde C, Papp K, Poulin Y, Vender R, Wiseman MC

Category: Psoriasis


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Date: August 1, 2017

Title: The Static Physician's Global Assessment of Genitalia: A Clinical Outcome Measure for the Severity of Genital Psoriasis

Authors: Merola JF, Bleakman AP, Gottlieb AB, Menter A, Naegeli AN, Bissonnette R, Guenther L, Sullivan J, Meeuwis K, See K, Duffin KC

Category: Psoriasis


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Date: July 31, 2017

Title: Topical treatment of psoriasis: questionnaire results on topical therapy accessibility and in?uence of body surface area on usage

Authors: Iversen L, Lange MM, Bissonette R, Carvalho AVE, van de Kerkhof PC, Kirby B, Kleyn CE, Lynde CW, van der Walt JM, Wu JJ

Category: Psoriasis


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Date: July 15, 2017

Title: Increased frequencies of basophils, type 2 innate lymphoid cells and Th2 cells in skin of patients with atopic dermatitis but not psoriasis

Authors: Mashiko S, Mehta H, Bissonnette R, Sarfati M

Category: Dermatitis (all types)


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Date: July 1, 2017

Title: Persistence of interleukin (IL)-17A+ T lymphocytes and IL-17A expression in treatment-resistant psoriatic plaques despite ustekinumab therapy

Authors: Jack C, Mashiko S, Arbour N, Bissonnette R, Sarfati M

Category: Psoriasis


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Date: June 5, 2017

Title: Secukinumab Sustains Good Efficacy and Favourable Safety in Moderate to Severe Psoriasis up to 3 Years of Treatment: Results from A Double-Blind Extension Study

Authors: Bissonnette R, Luger T, Thaçi D, Toth D, Messina I, You R, Guana A, Fox T, Papavassilis C, Gilloteau I, Mrowietz U

Category: Psoriasis


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Date: June 1, 2017

Title: Prospective Study of Pathogenesis of Atrophic Acne Scars and Role of Macular Erythema

Authors: Tan J, Bourdès V, Bissonnette R, Petit B Eng L, Reynier P, Khammari A, Dreno B

Category: Acne


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Date: April 3, 2017

Title: Adapalene 0.1%/benzoyl peroxide 2.5% gel reduces the risk of atrophic scar formation in moderate inflammatory acne: a split-face randomized controlled trial.

Authors: Dreno B, Tan J, Rivier M, Martel P, Bissonnette R

Category: Acne


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Date: March 17, 2017

Title: Increase in coronary atherosclerosis severity and the prevalence of coronary artery mixed plaques in patients with psoriasis.

Authors: Bissonnette R, Cademartiti F, Maffei E, Tardif JC

Category: Psoriasis


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Date: March 9, 2017

Title: TNF-alpha antagonist and vascular inflammation in patients with psoriasis vulgaris: a randomized placebo-controlled study.

Authors: Bissonnette R, Harel F, Krueger JG, Guertin MC, Chabot-Blanchet M, Gonzalez J, Maari C, Delorme I, Lynde CW, Tardif JC

Category: Psoriasis


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Date: March 7, 2017

Title: Short- and long-term safety outcomes with ixekizumab from 7 clinical trials in psoriasis: Etanercept comparisons and integrated data.

Authors: Strober B, Leonardi C, Papp KA, Mrowietz U, Ohtsuki M, Bissonnette R, Ferris LK, Paul C, Lebwohl M, Braun DK, Mallbris L, Wilhelm S, Xu W, Ljungberg A, Acharya N, Reich K

Category: Psoriasis


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Date: February 24, 2017

Title: Molecular signatures order the potency of topically applied anti-inflammatory drugs in patients with atopic dermatitis.

Authors: Guttman-Yassky E, Ungar B, Malik K, Dickstein D, Suprun M, Estrada YD, Xu H, Peng X, Oliva M, Todd D, Labuda T, Suarez-Farinas M, Bissonnette R

Category: Dermatitis (all types)


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Date: January 8, 2017

Title: Palmoplantar pustular psoriasis (PPPP) is characterized by activation of the IL-17A pathway.

Authors: Bissonnette R, Fuentes-Duculan J, Mashiko S, Li X, Bonifacio KM, Cueto I, Suárez-Fariñas M, Maari C, Bolduc C, Nigen S, Sarfati M, Krueger JG

Category: Psoriasis


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Date: January 7, 2017

Title: Olumacostat glasaretil, a novel topical sebum inhibitor, in the treatment of acne vulgaris: A phase IIa, multicenter, randomized, vehicle-controlled study.

Authors: Bissonnette R, Poulin Y, Drew J, Hofland H, Tan J

Category: Acne


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Date: December 6, 2016

Title: Use of Lesion Response Rate in Actinic Keratosis Trials.

Authors: Szeimies RM, Atanasov P, Bissonnette R

Category: Actinic Keratoses


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Date: November 17, 2016

Title: Topical tofacitinib for atopic dermatitis: a phase IIa randomized trial.

Authors: Bissonnette R, Papp KA, Poulin Y, Gooderham M, Raman M, Mallbris L, Wang C, Purohit V, Mamolo C, Papacharalambous J, Ports WC

Category: Dermatitis (all types)


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Date: November 13, 2016

Title: The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, but with Key Differences in Immune Regulatory Genes.

Authors: Kim J, Bissonnette R, Lee J, Correa da Rosa J, Suárez-Fariñas M, Lowes MA, Krueger JG

Category: Psoriasis


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Date: October 3, 2016

Title: Treatment of plaque psoriasis with an ointment formulation of the Janus kinase inhibitor, tofacitinib: a Phase 2b randomized clinical trial.

Authors: Papp KA, Bissonnette R, Gooderham M, Feldman SR, Iversen L, Soung J, Draelos Z, Mamolo C, Purohit V, Wang C, Ports WC

Category: Psoriasis


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Date: August 27, 2016

Title: A randomized, double-blind, placebo-controlled, dose-escalation study of the safety and efficacy of INCB039110, an oral janus kinase 1 inhibitor, in patients with stable, chronic plaque psoriasis

Authors: Bissonnette R, Luchi M, Fidelus-Gort R, Jackson S, Zhang H, Flores R, Newton R, Scherle P, Yeleswaram S, Chen X, Menter A

Category: Psoriasis


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Date: July 30, 2016

Title: Identification of key research needs for topical therapy treatment of psoriasis - a consensus paper by the International Psoriasis Council

Authors: Wu JJ, Lynde CW, Kleyn CE, Iversen L, van der Walt JM, Carvalho A, Kirby B, Bissonnette R

Category: Psoriasis


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Date: July 16, 2016

Title: Topical tofacitinib for atopic dermatitis: A Phase 2a randomised trial

Authors: Bissonnette R, Papp KA, Poulin Y, Gooderham M, Raman M, Mallbris L, Wang C, Purohit V, Mamolo C, Papacharalambous J, Ports WC

Category: Dermatitis (all types)


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Date: July 7, 2016

Title: Apremilast, an oral phosphodiesterase-4 inhibitor, in the treatment of palmoplantar psoriasis: Results of a pooled analysis from phase II PSOR-005 and phase III Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis (ESTEEM) clinical trials in patients with moderate to severe psoriasis

Authors: Bissonnette R, Pariser DM, Wasel NR, Goncalves J, Day RM, Chen R, Sebastian M

Category: Psoriasis


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Date: July 2, 2016

Title: Correction: Based on Molecular Profiling of Gene Expression, Palmoplantar Pustulosis and Palmoplantar Pustular Psoriasis Are Highly Related Diseases that Appear to Be Distinct from Psoriasis Vulgaris

Authors: Bissonnette R, Suárez-Fariñas M, Li X, Bonifacio KM, Brodmerkel C, Fuentes-Duculan J, Krueger JG

Category: Psoriasis


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Date: May 20, 2016

Title: Psoriasis and Smoking: A Systematic Literature Review and Meta-Analysis With Qualitative Analysis of Effect of Smoking on Psoriasis Severity

Authors: Richer V, Roubille C, Fleming P, Starnino T, McCourt C, McFarlane A, Siu S, Kraft J, Lynde C, Pope JE, Keeling S, Dutz J, Bessette L, Gulliver WP, Haraoui B, Bissonnette R

Category: Psoriasis


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Date: May 13, 2016

Title: The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, but with Key Differences in Immune Regulatory Genes

Authors: Kim J, Bissonnette R, Lee J, Correa da Rosa J, Suárez-Fariñas M, Lowes MA, Krueger JG

Category: Psoriasis


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Date: May 7, 2016

Title: Comparative effectiveness of biologic agents for the treatment of psoriasis in a real-world setting: Results from a large, prospective, observational study (Psoriasis Longitudinal Assessment and Registry [PSOLAR]).

Authors: Strober BE, Bissonnette R, Fiorentino D, Kimball AB, Naldi L, Shear NH, Goyal K, Fakharzadeh S, Calabro S, Langholff W, You Y, Galindo C, Lee S, Lebwohl MG

Category: Psoriasis


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Date: May 6, 2016

Title: Based on Molecular Profiling of Gene Expression, Palmoplantar Pustulosis and Palmoplantar Pustular Psoriasis Are Highly Related Diseases that Appear to Be Distinct from Psoriasis Vulgaris

Authors: Bissonnette R, Suárez-Fariñas M, Li X, Bonifacio KM, Brodmerkel C, Fuentes-Duculan J, Krueger JG

Category: Psoriasis


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Date: May 4, 2016

Title: Dr. Roubille, et al reply

Authors: Roubille C, Richer V, Starnino T, McCourt C, McFARLANE A, Fleming P, Siu S, Kraft J, Lynde C, Pope JE, Gulliver W, Keeling S, Dutz J, Bessette L, Bissonnette R, Haraoui B

Category: Other


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Date: April 6, 2016

Title: Systematic review of efficacy of anti-tumor necrosis factor (TNF) therapy in patients with psoriasis previously treated with a different anti-TNF agent

Authors: Yamauchi PS, Bissonnette R, Teixeira HD, Valdecantos WC

Category: Psoriasis


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Date: August 14, 2015

Title: Randomized Pilot Clinical Trial of Tofacitinib Solution for Plaque Psoriasis: Challenges of the Intra-Subject Study Design.

Authors: Ports WC, Feldman SR, Gupta P, Tan H, Johnson TR, Bissonnette R

Category: Psoriasis


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Date: July 15, 2015

Title: Evidence-based Recommendations for the Management of Comorbidities in Rheumatoid Arthritis, Psoriasis, and Psoriatic Arthritis: Expert Opinion of the Canadian Dermatology-Rheumatology Comorbidity Initiative.

Authors: Roubille C, Richer V, Starnino T, McCourt C, McFarlane A, Fleming P, Siu S, Kraft J, Lynde C, Pope J, Gulliver W, Keeling S, Dutz J, Bessette L, Bissonnette R, Haraoui B

Category: Psoriasis


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Date: July 9, 2015

Title: A Phase 2 Trial of Guselkumab versus Adalimumab for Plaque Psoriasis.

Authors: Gordon KB, Duffin KC, Bissonnette R, Prinz JC, Wasfi Y, Li S, Shen YK, Szapary P, Randazzo B, Reich K

Category: Psoriasis


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Date: May 16, 2015

Title: Secukinumab in psoriasis: randomized, controlled phase 3 trial results assessing the potential to improve treatment response in partial responders (STATURE).

Authors: Thaçi D, Humeniuk J, Frambach Y, Bissonnette R, Goodman JJ, Shevade S, Gong Y, Papavassilis C; STATURE study group

Category: Psoriasis


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Date: May 8, 2015

Title: Evidence that a neutrophil-keratinocyte crosstalk is an early target of IL-17A inhibition in psoriasis.

Authors:

Category: Psoriasis


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Date: May 1, 2015

Title: Meta-analysis of tumor necrosis factor inhibitors and glucocorticoids on bone density in rheumatoid arthritis and ankylosing spondylitis trials

Authors: Siu S, Haraoui B, Bissonnette R, Bessette L, Roubille C, Richer V, Starnino T, McCourt C, McFarlane A, Fleming P, Kraft J, Lynde C, Gulliver W, Keeling S, Dutz J, Pope JE

Category: Other


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Date: April 2, 2015

Title: Tofacitinib withdrawal and retreatment in moderate-to-severe chronic plaque psoriasis: a randomized controlled trial

Authors: Bissonnette R, Iversen L, Sofen H, Griffiths CE, Foley P, Romiti R, Bachinsky M, Rottinghaus ST, Tan H, Proulx J, Valdez H, Gupta P, Mallbris L, Wolk R

Category: Psoriasis


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Date: March 24, 2015

Title: IL-23/IL-17A Dysfunction Phenotypes Inform Possible Clinical Effects from Anti-IL-17A Therapies.

Authors: Blauvelt A, Lebwohl MG, Bissonnette R

Category: Other


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Date: March 16, 2015

Title: Human mast cells are major IL-22 producers in patients with psoriasis and atopic dermatitis.

Authors: Mashiko S, Bouguermouh S, Rubio M, Baba N, Bissonnette R, Sarfati M

Category: Psoriasis


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Date: March 9, 2015

Title: Response to: 'drugs and cardiovascular risk in inflammatory arthritis: another case of glucocorticoid-bashing?' by Dr Boers.

Authors: Roubille C, Richer V, Starnino T, McCourt C, McFarlane A, Fleming P, Siu S, Kraft J, Lynde C, Pope J, Gulliver W, Keeling S, Dutz J, Bessette L, Bissonnette R, Haraoui B

Category: Other


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Date: February 28, 2015

Title: A Randomized, blinded assessor study to Evaluate the efFIcacy and safety of etanercept 50 mg once weekly plus as Needed topical agent vs. Etanercept 50 mg twice weekly in patients with moderate to severe plaque psoriasis (REFINE)

Authors: Papp KA, Barber K, Bissonnette R, Bourcier M, Lynde CW, Poulin Y, Shelton J, Toole J, Vieira A, Poulin-Costello M

Category: Psoriasis


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Date: January 21, 2015

Title: Improvements in patient-reported outcomes in patients with psoriasis receiving etanercept plus topical therapies: results from REFINE.

Authors: Papp KA, Barber K, Bissonnette R, Bourcier M, Lynde CW, Poulin Y, Shelton J, Garces K, Toole J, Poulin-Costello M

Category: Psoriasis


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Date: January 20, 2015

Title: Etanercept for patients with psoriasis who did not respond or who lost their response to adalimumab or infliximab.

Authors: Bissonnette R, Maari C, Barber K, Lynde CW, Vender R

Category: Psoriasis


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Date: January 5, 2015

Title: The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis, psoriasis and psoriatic arthritis: a systematic review and meta-analysis.

Authors: Roubille C, Richer V, Starnino T, McCourt C, McFarlane A, Fleming P, Siu S, Kraft J, Lynde C, Pope J, Gulliver W, Keeling S, Dutz J, Bessette L, Bissonnette R, Haraoui B

Category: Psoriasis


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Date: December 10, 2014

Title: Effect of biologics on depressive symptoms in patients with psoriasis: a systematic review.

Authors: Fleming P, Roubille C, Richer V, Starnino T, McCourt C, McFarlane A, Siu S, Kraft J, Lynde C, Pope JE, Keeling S, Dutz J, Bessette L, Bissonnette R, Haraoui B, Gulliver WP

Category: Psoriasis


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Date: October 1, 2014

Title: Increased expression of IL-17A and limited involvement of IL-23 in patients with palmo-plantar (PP) pustular psoriasis or PP pustulosis; results from a randomised controlled trial.

Authors: Bissonnette R, Nigen S, Langley RG, Lynde CW, Tan J, Fuentes-Duculan J, Krueger JG

Category: Psoriasis


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Date: August 28, 2014

Title: Changes in serum free testosterone, sleep patterns, and 5-alpha-reductase type I activity influence changes in sebum excretion in female subjects.

Authors: Bissonnette R, Risch JE, McElwee KJ, Marchessault P, Bolduc C, Nigen S, Maari C

Category: Other


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Date: August 26, 2014

Title: Open-label exploratory study of acitretin for the treatment of severe chronic hand dermatitis.

Authors: Tan J, Maari C, Nigen S, Bolduc C, Bissonnette R

Category: Dermatitis (all types)


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Date: July 1, 2014

Title: A Randomized, blinded assessor study to Evaluate the efFIcacy and safety of etanercept 50 mg once weekly plus as Needed topical agent vs. Etanercept 50 mg twice weekly in patients with moderate to severe plaque psoriasis (REFINE).

Authors: Papp KA, Barber K, Bissonnette R, Bourcier M, Lynde CW, Poulin Y, Shelton J, Toole J, Vieira A, Poulin-Costello M

Category: Psoriasis


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Date: June 1, 2014

Title: Treatment of notalgia paresthetica with botulinum toxin A: a double-blind randomized controlled trial.

Authors: Maari C, Marchessault P, Bissonnette R

Category: Other


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Date: December 1, 2013

Title: Long-term efficacy of ustekinumab in patients with moderate-to-severe psoriasis treated for up to 5 years in the PHOENIX 1 study.

Authors: Kimball AB, Papp KA, Wasfi Y, Chan D, Bissonnette R, Sofen H, Yeilding N, Li S, Szapary P, Gordon KB; PHOENIX 1 Investigators

Category: Psoriasis


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Date: November 1, 2013

Title: Risk of myocardial infarction in Canadian patients with psoriasis: a retrospective cohort study.

Authors: Levesque A, Lachaine J, Bissonnette R

Category: Psoriasis


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Date: July 16, 2013

Title: A randomized phase 2a efficacy and safety trial of the topical Janus kinase inhibitor tofacitinib in the treatment of chronic plaque psoriasis.

Authors: Ports WC, Khan S, Lan S, Lamba M, Bolduc C, Bissonnette R, Papp K

Category: Psoriasis


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Date: April 13, 2013

Title: Consensus recommendations for the treatment of basal cell carcinomas in Gorlin syndrome with topical methylaminolaevulinate-photodynamic therapy.

Authors: Basset-Seguin N, Bissonnette R, Girard C, Haedersdal M, Lear JT, Paul C, Piaserico S

Category: Other


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Date: January 1, 2013

Title: Effects of the tumor necrosis factor-? antagonist adalimumab on arterial inflammation assessed by positron emission tomography in patients with psoriasis: results of a randomized controlled trial.

Authors: Bissonnette R, Tardif JC, Harel F, Pressacco J, Bolduc C, Guertin MC

Category: Psoriasis


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Date: December 26, 2012

Title: Efficacy and safety of topical WBI-1001 in patients with mild to moderate psoriasis: results from a randomized double-blind placebo-controlled, phase II trial.

Authors: Bissonnette R, Bolduc C, Maari C, Nigen S, Webster JM, Tang L, Lyle M

Category: Psoriasis


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Date: December 6, 2012

Title: Short incubation photodynamic therapy with methylaminolevulinate and no occlusion for the treatment of actinic keratoses.

Authors: Bissonnette R, Bolduc C, Maari C, Nigen S

Category: Actinic Keratoses


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Date: October 28, 2012

Title: Influence of the quantity of sunscreen applied on the ability to protect against ultraviolet-induced polymorphous light eruption.

Authors: Bissonnette R, Nigen S, Bolduc C

Category: Other


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Date: September 26, 2012

Title: Photodynamic therapy for skin field cancerization: an international consensus. International Society for Photodynamic Therapy in Dermatology.

Authors: Braathen LR, Morton CA, Basset-Seguin N, Bissonnette R, Gerritsen MJ, Gilaberte Y, Calzavara-Pinton P, Sidoroff A, Wulf HC, Szeimies RM

Category: Other


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Date: September 19, 2012

Title: Effect of adalimumab on sleep parameters in patients with psoriasis and obstructive sleep apnea: a randomized controlled trial.

Authors: Maari C, Bolduc C, Nigen S, Marchessault P, Bissonnette R

Category: Psoriasis


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Date: August 23, 2012

Title: A randomized study comparing the combination of nbUVB and etanercept to etanercept monotherapy in patients with psoriasis who do not exhibit an excellent response after 12 weeks of etanercept.

Authors: Lynde CW, Gupta AK, Guenther L, Poulin Y, Levesque A, Bissonnette R

Category: Psoriasis


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Date: August 11, 2012

Title: A randomized controlled study of combination therapy with alefacept and narrow band UVB phototherapy (UVB) for moderate to severe psoriasis: efficacy, onset, and duration of response.

Authors: Lui H, Gulliver W, Tan J, Hong CH, Hull P, Shear NH, Paradiso-Hardy F, Bissonnette R

Category: Psoriasis


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Date: July 16, 2012

Title: Safety and efficacy of adalimumab for the treatment of severe alopecia areata: case series of three patients.

Authors: Bolduc C, Bissonnette R

Category: Other


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Date: June 26, 2012

Title: Daylight photodynamic therapy for actinic keratosis: an international consensus: International Society for Photodynamic Therapy in Dermatology.

Authors: Wiegell SR, Wulf HC, Szeimies RM, Basset-Seguin N, Bissonnette R, Gerritsen MJ, Gilaberte Y, Calzavara-Pinton P, Morton CA, Sidoroff A, Braathen LR

Category: Actinic Keratoses


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Date: April 16, 2012

Title: Efficacy and safety of topical WBI-1001 in patients with mild to severe atopic dermatitis: results from a 12-week, multicentre, randomized, placebo-controlled double-blind trial.

Authors: Bissonnette R, Poulin Y, Zhou Y, Tan J, Hong HC, Webster J, Ip W, Tang L, Lyle M

Category: Dermatitis (all types)


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Date: February 26, 2012

Title: Psoriasis: Why Does it Come With a Greater Risk of Heart Attack and Stroke?

Authors: Bissonnette R

Category: Psoriasis


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Date: February 6, 2012

Title: Assessment of the long-term safety and effectiveness of etanercept for the treatment of psoriasis in an adult population.

Authors: Papp KA, Poulin Y, Bissonnette R, Bourcier M, Toth D, Rosoph L, Poulin-Costello M, Setterfield M, Syrotuik J

Category: Psoriasis


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Date: December 25, 2011

Title: Treatment of palmoplantar psoriasis with infliximab: a randomized, double-blind placebo-controlled study.

Authors: Bissonnette R, Poulin Y, Guenther L, Lynde CW, Bolduc C, Nigen S

Category: Psoriasis


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Date: December 14, 2011

Title: Treatment of acne with photodynamic therapy.

Authors: Bissonnette R

Category: Acne


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Date: November 8, 2011

Title: Fatigue and quality of sleep in patients with immune-mediated inflammatory disease.

Authors: Graff LA, Walker JR, Russell AS, Bissonnette R, Bernstein CN

Category: Other


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Date: November 8, 2011

Title: Validity of quality of life measurement tools--from generic to disease-specific.

Authors: Wells GA, Russell AS, Haraoui B, Bissonnette R, Ware CF

Category: Other


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Date: November 3, 2011

Title: Socioeconomic burden of immune-mediated inflammatory diseases--focusing on work productivity and disability.

Authors: Jacobs P, Bissonnette R, Guenther LC

Category: Other


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Date: September 10, 2011

Title: Randomized trial comparing a chemical peel containing a lipophilic hydroxy acid derivative of salicylic acid with a salicylic acid peel in subjects with comedonal acne.

Authors: Levesque A, Hamzavi I, Seite S, Rougier A, Bissonnette R

Category: Acne


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Date: August 15, 2011

Title: Support needed to involve psoriasis patients in treatment decisions: survey of dermatologists.

Authors: Tan J, Stacey D, Barankin B, Bissonnette R, Gulliver W, Lui H, Shear N, Bhatti S

Category: Psoriasis


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Date: May 15, 2011

Title: Short incubation methylaminolevulinate photodynamic therapy without occlusion for the treatment of actinic keratoses

Authors: Robert Bissonnette, MD, FRCPC Simon Nigen, MD, FRCPC Chantal Bolduc, MD, FRCPC Catherine Maari, MD, FRCPC

Category: Actinic Keratoses


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Date: March 3, 2011

Title: An open-label study assessing the safety and efficacy of alitretinoin in patients with severe chronic hand eczema unresponsive to topical corticosteroids.

Authors: Dirschka T, Reich K, Bissonnette R, Maares J, Brown T, Diepgen TL

Category: Eczema


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Date: December 14, 2010

Title: Canadian hand dermatitis management guidelines.

Authors: Lynde C, Guenther L, Diepgen TL, Sasseville D, Poulin Y, Gulliver W, Agner T, Barber K, Bissonnette R, Ho V, Shear NH, Toole J

Category: Dermatitis (all types)


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Date: November 9, 2010

Title: Photodynamic therapy with methylaminolevulinate 80 mg/g without occlusion improves acne vulgaris.

Authors: Bissonnette R, Maari C, Nigen S, Provost N, Bolduc C

Category: Acne


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Date: October 14, 2010

Title: Treatment decision needs of psoriasis patients: cross-sectional survey.

Authors: Tan J, Stacey D, Fung K, Barankin B, Bissonnette R, Gulliver W, Lui H, Shear N, Jackson C, Zhang X

Category: Psoriasis


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Date: July 4, 2010

Title: Safety profile of intravenous and subcutaneous siplizumab, an anti-CD2 monoclonal antibody, for the treatment of plaque psoriasis: results of two randomized, double-blind, placebo-controlled studies.

Authors: Langley RG, Papp K, Bissonnette R, Toth D, Matheson R, Hultquist M, White B

Category: Psoriasis


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Date: May 24, 2010

Title: Redefining treatment options in chronic hand eczema (CHE).

Authors: Bissonnette R, Diepgen TL, Elsner P, English J, Graham-Brown R, Homey B, Luger T, Lynde C, Maares J, Maibach HI

Category: Eczema


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Date: May 21, 2010

Title: Clobetasol propionate shampoo 0.05% is efficacious and safe for long-term control of moderate scalp psoriasis.

Authors: Poulin Y, Papp K, Bissonnette R, Barber K, Kerrouche N, Villemagne H; Calepso Study Team

Category: Psoriasis


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Date: May 20, 2010

Title: Efficacy and safety of adalimumab in patients with plaque psoriasis who have shown an unsatisfactory response to etanercept.

Authors: Bissonnette R, Bolduc C, Poulin Y, Guenther L, Lynde CW, Maari C

Category: Psoriasis


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Date: April 14, 2010

Title: Efficacy and safety of topical WBI-1001 in the treatment of atopic dermatitis: results from a phase 2A, randomized, placebo-controlled clinical trial.

Authors: Bissonnette R, Chen G, Bolduc C, Maari C, Lyle M, Tang L, Webster J, Zhou Y

Category: Dermatitis (all types)


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Date: March 9, 2010

Title: A double-blind study of tolerance and efficacy of a new urea-containing moisturizer in patients with atopic dermatitis.

Authors: Bissonnette R, Maari C, Provost N, Bolduc C, Nigen S, Rougier A, Seite S

Category: Dermatitis (all types)


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Date: March 6, 2010

Title: A randomized, double-blind, placebo-controlled, phase I study of MEDI-545, an anti-interferon-alfa monoclonal antibody, in subjects with chronic psoriasis.

Authors: Bissonnette R, Papp K, Maari C, Yao Y, Robbie G, White WI, Le C, White B

Category: Psoriasis


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Date: February 1, 2010

Title: Successful retreatment with alitretinoin in patients with relapsed chronic hand eczema.

Authors: Bissonnette R, Worm M, Gerlach B, Guenther L, Cambazard F, Ruzicka T, Maares J, Brown TC

Category: Eczema


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Date: January 8, 2010

Title: Clobetasol propionate shampoo 0.05% is efficacious and safe for long-term control of scalp psoriasis.

Authors: Poulin Y, Papp K, Bissonnette R, Guenther L, Tan J, Lynde C, Kerrouche N, Villemagne H; CalePso Study Team

Category: Psoriasis


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Date: December 13, 2009

Title: The next phase of real-world clinical experience with alefacept: the AWARE-2 registry

Authors: Searles G, Bissonnette R, Landells I, Shear NH

Category: Other


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Date: December 13, 2009

Title: Efficacy outcomes in patients using alefacept in the AWARE study

Authors: Landells I, Searles G, Bissonnette R, Shear NH, Vender R, Lui H

Category: Other


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Date: December 13, 2009

Title: Patterns of combination therapy with alefacept for the treatment of psoriasis in Canada in the AWARE study

Authors: Searles G, Bissonnette R, Landells I, Shear NH, Papp K, Lui H

Category: Psoriasis


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Date: December 13, 2009

Title: Update on alefacept safety

Authors: Wexler D, Searles G, Landells I, Shear NH, Bissonnette R, Papp K, Poulin Y, Langley R, Gulliver WP

Category: Psoriasis


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Date: December 13, 2009

Title: Preface: real-world clinical experience with alefacept-the Amevive Wisdom Acquired from Real-World Evidence (AWARE) study

Authors: Searles G, Bissonnette R, Landells I, Shear NH

Category: Other


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Date: December 13, 2009

Title: The AWARE study: methodology and baseline characteristics.

Authors: Bissonnette R, Searles G, Landells I, Shear NH, Papp K, Lui H, Gulliver WP, Lynde C

Category: Other


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Date: October 13, 2009

Title: Safety of conventional systemic agents and biologic agents in the treatment of psoriasis.

Authors: Bissonnette R, Ho V, Langley RG

Category: Psoriasis


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Date: July 30, 2009

Title: Humanized anti-CD2 monoclonal antibody treatment of plaque psoriasis: efficacy and pharmacodynamic results of two randomized, double-blind, placebo-controlled studies of intravenous and subcutaneous siplizumab.

Authors: Bissonnette R, Langley RG, Papp K, Matheson R, Toth D, Hultquist M, Geba GP, White B

Category: Psoriasis


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Date: March 8, 2009

Title: Randomized study comparing the efficacy and tolerance of a lipophillic hydroxy acid derivative of salicylic acid and 5% benzoyl peroxide in the treatment of facial acne vulgaris.

Authors: Bissonnette R, Bolduc C, Seité S, Nigen S, Provost N, Maari C, Rougier A

Category: Acne


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Date: October 12, 2008

Title: Efficacy and tolerability of topical tacrolimus ointment for the treatment of male genital psoriasis.

Authors: Bissonnette R, Nigen S, Bolduc C

Category: Psoriasis


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Date: October 7, 2008

Title: Etanercept in the treatment of palmoplantar pustulosis.

Authors: Bissonnette R, Poulin Y, Bolduc C, Maari C, Provost N, Syrotuik J, Poulin-Costello CM, Nigen S

Category: Other


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Date: September 15, 2008

Title: Protection afforded by sunscreens containing inorganic sunscreening agents against blue light sensitivity induced by aminolevulinic acid

Authors: Bissonnette R, Nigen S, Bolduc C, Méry S, Nocera T

Category: Acne


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Date: June 12, 2008

Title: Open-label study to assess the safety and efficacy of imiquimod 5% cream applied once daily three times per week in cycles for treatment of actinic keratoses on the head.

Authors: Rivers JK, Rosoph L, Provost N, Bissonnette R

Category: Actinic Keratoses


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Date: April 19, 2008

Title: Efficacy of ISA247 in plaque psoriasis: a randomised, multicentre, double-blind, placebo-controlled phase III study.

Authors: Papp K, Bissonnette R, Rosoph L, Wasel N, Lynde CW, Searles G, Shear NH, Huizinga RB, Maksymowych WP

Category: Psoriasis


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Date: April 15, 2008

Title: Efficacy and safety of oral alitretinoin (9-cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double-blind, placebo-controlled, multicentre trial.

Authors:

Category: Eczema


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Date: February 3, 2004

Title: Large surface photodynamic therapy with aminolevulinic acid: treatment of actinic keratoses and beyond

Authors: Bergeron A, Bissonette R, Liu Y

Category: Actinic Keratoses


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