Notalgia Paresthetica (NP) Case Study

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PPP rescue case study


Study Characteristics

  • Study Phase: II
  • Patient Population: 126 patients with Notalgia Paresthetica (NP) (Pruritus associated with NP)
  • IP Route of Administration: Systemic (oral)
  • Site Distribution: 33 sites (USA and Canada)
  • Study Procedures: Photographs, Pharmacokinetics, Electrocardiograms



Study Challenges

  • Patient awareness: Challenge in advertisement as patients are often unaware of the name of their condition
  • Run-in period (screening): To ensure the enrollment of highly compliant patients and those with consistent itch
  • Patient compliance: Primary endpoints were relying on patient-reported assessments
  • Uncommon indication: PI with little experience in this indication



Study Highlights

Site engagement Increased support for low-performing sites

Engaged with low-enrolling sites to ensure proper use of their local campaign budget

Phone interview icon Creative advertising

Digital and local innovative marketing tactics to encourage patients to participate

Dermatology Investigator Icon Notalgia paresthetica cro specialty

Innovaderm managed 100% of the notalgia paresthetica studies (as per clinical

Dermatology Investigator Icon High compliance rate

Additional patient compensation for fully completed diary

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